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Current review of surgical management options for extremity bone sarcomas
Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy.All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation....
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Published in: | EFORT Open Reviews 2019-05, Vol.4 (5), p.174-182 |
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creator | Cirstoiu, Catalin Cretu, Bogdan Serban, Bogdan Panti, Zsombor Nica, Mihai |
description | Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy.All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation.The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty.Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres.Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article:
2019;4:174-182. DOI: 10.1302/2058-5241.4.180048. |
doi_str_mv | 10.1302/2058-5241.4.180048 |
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2019;4:174-182. DOI: 10.1302/2058-5241.4.180048.</description><identifier>ISSN: 2058-5241</identifier><identifier>ISSN: 2396-7544</identifier><identifier>EISSN: 2058-5241</identifier><identifier>DOI: 10.1302/2058-5241.4.180048</identifier><identifier>PMID: 31191985</identifier><language>eng</language><publisher>England: BioScientifica Ltd</publisher><subject>Amputation ; Arthrodesis ; Bone cancer ; Bone grafts ; Bone Sarcoma ; Bone surgery ; Bone tumors ; Chemotherapy ; Modular Endoprostheses ; Oncology ; Reconstruction ; Sarcoma</subject><ispartof>EFORT Open Reviews, 2019-05, Vol.4 (5), p.174-182</ispartof><rights>2019. This work is published under https://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2019 The author(s) 2019 The author(s)</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-2f4d3e663bf754028e9b85774a12369600f0a08a292c2db124289d9c708f6b003</citedby><cites>FETCH-LOGICAL-c430t-2f4d3e663bf754028e9b85774a12369600f0a08a292c2db124289d9c708f6b003</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540945/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31191985$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cirstoiu, Catalin</creatorcontrib><creatorcontrib>Cretu, Bogdan</creatorcontrib><creatorcontrib>Serban, Bogdan</creatorcontrib><creatorcontrib>Panti, Zsombor</creatorcontrib><creatorcontrib>Nica, Mihai</creatorcontrib><title>Current review of surgical management options for extremity bone sarcomas</title><title>EFORT Open Reviews</title><addtitle>EFORT Open Rev</addtitle><description>Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy.All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation.The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty.Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres.Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article:
2019;4:174-182. DOI: 10.1302/2058-5241.4.180048.</description><subject>Amputation</subject><subject>Arthrodesis</subject><subject>Bone cancer</subject><subject>Bone grafts</subject><subject>Bone Sarcoma</subject><subject>Bone surgery</subject><subject>Bone tumors</subject><subject>Chemotherapy</subject><subject>Modular Endoprostheses</subject><subject>Oncology</subject><subject>Reconstruction</subject><subject>Sarcoma</subject><issn>2058-5241</issn><issn>2396-7544</issn><issn>2058-5241</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdkctOwzAQRS0EolXpD7BAltiwSRk_4jgbJFTxqITEBtaWkzglVRIXOyn073HUUhVWHnnu3HkchC4JzAgDekshllFMOZnxGZEAXJ6g8eHz9Cgeoan3KwAgScy4YOdoxAhJSSrjMVrMe-dM22FnNpX5wrbEvnfLKtc1bnSrl6YZsnbdVbb1uLQOm-_OmabqtjizrcFeu9w22l-gs1LX3kz37wS9Pz68zZ-jl9enxfz-Jco5gy6iJS-YEYJlZRJzoNKkmYyThGtCmUgFQAkapKYpzWmREcqpTIs0T0CWIgNgE3S38133WWOKPIzndK3Wrmq02yqrK_U301Yfamk3SoR2KY-Dwc3ewNnP3vhONZXPTV3r1tjeK8p4OGfMEhGk1_-kK9u7NqwXVAQ4T4QgQUV3qtxZ750pD8MQUAMsNbBQAwvF1Q5WKLo6XuNQ8ouG_QCibI6d</recordid><startdate>20190501</startdate><enddate>20190501</enddate><creator>Cirstoiu, Catalin</creator><creator>Cretu, Bogdan</creator><creator>Serban, Bogdan</creator><creator>Panti, Zsombor</creator><creator>Nica, Mihai</creator><general>BioScientifica Ltd</general><general>British Editorial Society of Bone and Joint Surgery</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190501</creationdate><title>Current review of surgical management options for extremity bone sarcomas</title><author>Cirstoiu, Catalin ; Cretu, Bogdan ; Serban, Bogdan ; Panti, Zsombor ; Nica, Mihai</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c430t-2f4d3e663bf754028e9b85774a12369600f0a08a292c2db124289d9c708f6b003</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Amputation</topic><topic>Arthrodesis</topic><topic>Bone cancer</topic><topic>Bone grafts</topic><topic>Bone Sarcoma</topic><topic>Bone surgery</topic><topic>Bone tumors</topic><topic>Chemotherapy</topic><topic>Modular Endoprostheses</topic><topic>Oncology</topic><topic>Reconstruction</topic><topic>Sarcoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cirstoiu, Catalin</creatorcontrib><creatorcontrib>Cretu, Bogdan</creatorcontrib><creatorcontrib>Serban, Bogdan</creatorcontrib><creatorcontrib>Panti, Zsombor</creatorcontrib><creatorcontrib>Nica, Mihai</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>EFORT Open Reviews</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cirstoiu, Catalin</au><au>Cretu, Bogdan</au><au>Serban, Bogdan</au><au>Panti, Zsombor</au><au>Nica, Mihai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Current review of surgical management options for extremity bone sarcomas</atitle><jtitle>EFORT Open Reviews</jtitle><addtitle>EFORT Open Rev</addtitle><date>2019-05-01</date><risdate>2019</risdate><volume>4</volume><issue>5</issue><spage>174</spage><epage>182</epage><pages>174-182</pages><issn>2058-5241</issn><issn>2396-7544</issn><eissn>2058-5241</eissn><abstract>Modern surgical management of extremity bone sarcomas is governed by limb-sparing surgery combined with adjuvant and neoadjuvant chemotherapy.All the resection and reconstruction techniques have to achieve oncologic excision margins, with survival rates and functional results superior to amputation.The main reconstruction techniques of bone defects resulted after resection are: modular endoprosthetic reconstruction; bone graft reconstruction; bone transport; resection arthrodesis; and rotationplasty.Oncologic resection and modular endoprosthetic reconstruction are the generally approved surgical options adopted for the majority of cases in major specialized bone sarcoma centres.Good basic principles, efficient multidisciplinary approach and sustained research in the field can provide a better future for the challenge posed by extremity bone sarcoma treatment. Cite this article:
2019;4:174-182. DOI: 10.1302/2058-5241.4.180048.</abstract><cop>England</cop><pub>BioScientifica Ltd</pub><pmid>31191985</pmid><doi>10.1302/2058-5241.4.180048</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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source | PubMed Central |
subjects | Amputation Arthrodesis Bone cancer Bone grafts Bone Sarcoma Bone surgery Bone tumors Chemotherapy Modular Endoprostheses Oncology Reconstruction Sarcoma |
title | Current review of surgical management options for extremity bone sarcomas |
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