Pros and Cons of Aspirin Prophylaxis for Prevention of Cardiovascular Events in Kidney Transplantation and Review of Evidence

Kidney transplant recipients have traditional and nontraditional risk factors which can lead to coronary artery disease and sudden death with a functional graft loss. Aspirin has been used traditionally for prevention of cardiovascular and cerebrovascular accidents. It has beneficial effects in seco...

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Bibliographic Details
Published in:Advances in preventive medicine 2019, Vol.2019 (2019), p.1-14
Main Authors: Tan, Jackson, Chong, Vui Heng, Rajput, Ahmed Suleman, Daiwajna, Rajendra Govindrao, Alam, Sartaj, Khamis, Said Sayed Ahmed, Khalil, Muhammad Shahab Ud Din, Khalil, Muhammad Abdul Mabood, Alhaji, Mohammed M.
Format: Article
Language:English
Subjects:
Analgesics
Aspirin
Cardiology
Cardiovascular disease
Clinical trials
Coronary heart disease
Diabetes
Disease prevention
Drug dosages
Drug therapy
Health risk assessment
Kidney diseases
Kidney transplants
Kidneys
Mortality
Organ transplant recipients
Prevention
Review
Stents
Stroke (Disease)
Systematic review
Thrombosis
Transplantation
Transplants & implants
Type 2 diabetes
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Summary:Kidney transplant recipients have traditional and nontraditional risk factors which can lead to coronary artery disease and sudden death with a functional graft loss. Aspirin has been used traditionally for prevention of cardiovascular and cerebrovascular accidents. It has beneficial effects in secondary prevention of cardiovascular events in general population. Its use for primary prophylaxis is still disputed. Bleeding and theoretical risk of nephrotoxicity are the major concerns about its use. The data on aspirin in kidney transplant population is sparse. This review will focus on various pros and cons of aspirin use for prevention of cardiovascular events in kidney transplant recipients and a way forward.
ISSN:2090-3480
2090-3499
2090-3499
DOI:10.1155/2019/6139253