A functional dissociation of face-, body- and scene-selective brain areas based on their response to moving and static stimuli

• Published in: Scientific reports 2019-06, Vol.9 (1), p.8242-8242, Article 8242
• Main Authors: Pitcher, David, Ianni, Geena, Ungerleider, Leslie G.
• Format: Article
• Language: English
• Subjects: 59; 59/36; 631/378/2613/2616; 631/378/2649/1723; Amygdala; Brain; Brain - anatomy & histology; Brain - physiology; Brain mapping; Face; Functional magnetic resonance imaging; Hemispheric laterality; Humanities and Social Sciences; Humans; Medical imaging; Movement; multidisciplinary; Neuroimaging; Parahippocampal gyrus; Photic Stimulation; Science; Science (multidisciplinary); Superior temporal sulcus; Variance analysis
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-019-44663-9

The human brain contains areas that respond selectively to faces, bodies and scenes. Neuroimaging studies have shown that a subset of these areas preferentially respond more to moving than static stimuli, but the reasons for this functional dissociation remain unclear. In the present study, we simultaneously mapped the responses to motion in face-, body- and scene-selective areas in the right hemisphere using moving and static stimuli. Participants (N = 22) were scanned using functional magnetic resonance imaging (fMRI) while viewing videos containing bodies, faces, objects, scenes or scrambled objects, and static pictures from the beginning, middle and end of each video. Results demonstrated that lateral areas, including face-selective areas in the posterior and anterior superior temporal sulcus (STS), the extrastriate body area (EBA) and the occipital place area (OPA) responded more to moving than static stimuli. By contrast, there was no difference between the response to moving and static stimuli in ventral and medial category-selective areas, including the fusiform face area (FFA), occipital face area (OFA), amygdala, fusiform body area (FBA), retrosplenial complex (RSC) and parahippocampal place area (PPA). This functional dissociation between lateral and ventral/medial brain areas that respond selectively to different visual categories suggests that face-, body- and scene-selective networks may be functionally organized along a common dimension.