Light-responsive nanomedicine for biophotonic imaging and targeted therapy

Nanoparticles (NPs) play a key role in nanomedicine in multimodal imaging, drug delivery and targeted therapy of human diseases. Consequently, due to the attractive properties of NPs including high stability, high payload, multifunctionality, design flexibility, and efficient delivery to target tiss...

Full description

Saved in:
Bibliographic Details
Published in:Advanced drug delivery reviews 2019-01, Vol.138, p.133-147
Main Authors: Son, Jihwan, Yi, Gawon, Yoo, Jihye, Park, Changhee, Koo, Heebeom, Choi, Hak Soo
Format: Article
Language:English
Subjects:
Animals
Diagnostic Imaging
Drug Delivery Systems
Humans
Light
Light-responsiveness
Nanomedicine
Nanostructures - administration & dosage
Nanostructures - radiation effects
Optical imaging
Targeted therapy
Theranostic Nanomedicine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Nanoparticles (NPs) play a key role in nanomedicine in multimodal imaging, drug delivery and targeted therapy of human diseases. Consequently, due to the attractive properties of NPs including high stability, high payload, multifunctionality, design flexibility, and efficient delivery to target tissues, nanomedicine employs various types of NPs to enhance targeting and treatment efficacy. In this review, we primarily focus on light-responsive materials, such as fluorophores, photosensitizers, semiconducting polymers, carbon structures, gold particles, quantum dots, and upconversion crystals, for their biomedical applications. Armed with these nanomaterials, NPs represent a growing potential in biophotonic imaging (luminescence, photoacoustic, surface enhanced Raman scattering, and optical coherence tomography) as well as targeted therapy (photodynamic therapy, photothermal therapy, and light-responsive drug release). [Display omitted]
ISSN:0169-409X
1872-8294
DOI:10.1016/j.addr.2018.10.002