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Nocturnal enuresis in obese children: a nation-wide epidemiological study from China
Childhood obesity increases the risk of obstructive sleep apnea syndrome, type 2 diabetes mellitus, cardiovascular abnormalities, and psychological and behavioral disorders. But it is unclear whether obesity is associated with childhood nocturnal enuresis (NE). This study aimed to assess the relatio...
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Published in: | Scientific reports 2019-06, Vol.9 (1), p.8414, Article 8414 |
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description | Childhood obesity increases the risk of obstructive sleep apnea syndrome, type 2 diabetes mellitus, cardiovascular abnormalities, and psychological and behavioral disorders. But it is unclear whether obesity is associated with childhood nocturnal enuresis (NE). This study aimed to assess the relationship between childhood obesity and NE in a nationally representative large sample in China. Subjects were enrolled from Urumqi, Chengdu, Xi’an, Hohhot, Wuhan, Canton, Shanghai, and Harbin cities in China in November and December 2005. The survey included 20,987 children aged 5–12 years and they and their caregivers completed questionnaires. Height and weight were measured by school teachers trained in healthcare. According to the WHO child growth standards, obesity was defined as a body mass index >95
th
percentile of peers with the same age and gender. NE was defined as bed wetting for more than twice a week for 3 consecutive months. Demographic variables were compared among different groups. The prevalence of obesity, asthma, attention-deficit/hyperactivity disorder (ADHD), depressive moods, and snoring were different between the NE and without-NE groups (P |
doi_str_mv | 10.1038/s41598-019-44532-5 |
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fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6557885</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2237861208</sourcerecordid><originalsourceid>FETCH-LOGICAL-c522t-54924f41bab3d16d89edfd88e71432bf6a7ed2e8885aed5b636c8dd58b0e29de3</originalsourceid><addsrcrecordid>eNp9kcFO3DAQhq2KqqAtL8ChstQLl9B4bCdOD5XQqqWVEFzgbDnxZNcosbd2AuLt8bJAKQd8GFuab37PzE_IEStPWMnVtySYbFRRsqYQQnIo5AdyAKWQBXCAvVfvfXKY0k2Zj4RGsOYT2eeMKagFHJCri9BNc_RmoOjniMkl6jwNLSak3doNNqL_Tg31ZnLBF3fOIsVNjqMLQ1i5Llemabb3tI9hpMu18-Yz-dibIeHh070g179-Xi1_F-eXZ3-Wp-dFJwGmQooGRC9Ya1puWWVVg7a3SmHNBIe2r0yNFlApJQ1a2Va86pS1UrUlQmORL8iPne5mbke0HfopmkFvohtNvNfBOP1_xru1XoVbXUlZZ9UscPwkEMPfGdOkR5c6HAbjMcxJAwhZ1UrkjS_I1zfoTXjc25bitaoYlCpTsKO6GFKK2L80w0q99U3vfNPZN_3om9528eX1GC8lzy5lgO-AlFN-hfHf3-_IPgC5eKSb</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2237861208</pqid></control><display><type>article</type><title>Nocturnal enuresis in obese children: a nation-wide epidemiological study from China</title><source>Publicly Available Content Database</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature - nature.com Journals - Fully Open Access</source><creator>Zhang, Anyi ; Li, Shenghui ; Zhang, Yiwen ; Jiang, Fan ; Jin, Xingming ; Ma, Jun</creator><creatorcontrib>Zhang, Anyi ; Li, Shenghui ; Zhang, Yiwen ; Jiang, Fan ; Jin, Xingming ; Ma, Jun</creatorcontrib><description>Childhood obesity increases the risk of obstructive sleep apnea syndrome, type 2 diabetes mellitus, cardiovascular abnormalities, and psychological and behavioral disorders. But it is unclear whether obesity is associated with childhood nocturnal enuresis (NE). This study aimed to assess the relationship between childhood obesity and NE in a nationally representative large sample in China. Subjects were enrolled from Urumqi, Chengdu, Xi’an, Hohhot, Wuhan, Canton, Shanghai, and Harbin cities in China in November and December 2005. The survey included 20,987 children aged 5–12 years and they and their caregivers completed questionnaires. Height and weight were measured by school teachers trained in healthcare. According to the WHO child growth standards, obesity was defined as a body mass index >95
th
percentile of peers with the same age and gender. NE was defined as bed wetting for more than twice a week for 3 consecutive months. Demographic variables were compared among different groups. The prevalence of obesity, asthma, attention-deficit/hyperactivity disorder (ADHD), depressive moods, and snoring were different between the NE and without-NE groups (P < 0.05). The raw odds ratio (OR) for NE and obesity was 1.36 (95%CI = 1.07–1.74; P = 0.013) and the adjusted OR was 1.42 (95%CI = 1.11–1.82; P = 0.005) in the multivariable analysis. When adjusting for co-occurring conditions, the results showed that asthma did not affect the risk of NE (OR = 1.42, 95%CI = 1.11–1.82; P = 0.005), but ADHD (OR = 1.41; 95%CI = 1.10–1.81; P = 0.006) and depressive moods (OR = 1.34; 95%CI = 1.07–1.76; P = 0.012) slightly weakens the association between NE in children and obesity, while snoring weakens the association between obesity and NE and the risk became non-significant (OR = 1.21; 95%CI = 0.94–1.56; P = 0.138). In conclusion, obese children were at a higher risk of incurring NE compared to non-obese children. This association was weaker in children who either snored, had ADHD, or had depressive mood.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-019-44532-5</identifier><identifier>PMID: 31182742</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699 ; 692/700 ; Apnea ; Asthma ; Attention deficit hyperactivity disorder ; Body mass index ; Child ; Children ; China - epidemiology ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Enuresis ; Epidemiology ; Female ; Humanities and Social Sciences ; Humans ; Hyperactivity ; Logistic Models ; Male ; Mental depression ; Mood ; multidisciplinary ; Multivariate Analysis ; Nocturnal ; Nocturnal Enuresis - complications ; Nocturnal Enuresis - epidemiology ; Nocturnal Enuresis - pathology ; Obesity ; Obesity - complications ; Risk Factors ; Science ; Science (multidisciplinary) ; Severity of Illness Index ; Sleep ; Sleep disorders</subject><ispartof>Scientific reports, 2019-06, Vol.9 (1), p.8414, Article 8414</ispartof><rights>The Author(s) 2019</rights><rights>The Author(s) 2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-54924f41bab3d16d89edfd88e71432bf6a7ed2e8885aed5b636c8dd58b0e29de3</citedby><cites>FETCH-LOGICAL-c522t-54924f41bab3d16d89edfd88e71432bf6a7ed2e8885aed5b636c8dd58b0e29de3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2237861208/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2237861208?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25752,27923,27924,37011,37012,44589,53790,53792,74897</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31182742$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhang, Anyi</creatorcontrib><creatorcontrib>Li, Shenghui</creatorcontrib><creatorcontrib>Zhang, Yiwen</creatorcontrib><creatorcontrib>Jiang, Fan</creatorcontrib><creatorcontrib>Jin, Xingming</creatorcontrib><creatorcontrib>Ma, Jun</creatorcontrib><title>Nocturnal enuresis in obese children: a nation-wide epidemiological study from China</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>Childhood obesity increases the risk of obstructive sleep apnea syndrome, type 2 diabetes mellitus, cardiovascular abnormalities, and psychological and behavioral disorders. But it is unclear whether obesity is associated with childhood nocturnal enuresis (NE). This study aimed to assess the relationship between childhood obesity and NE in a nationally representative large sample in China. Subjects were enrolled from Urumqi, Chengdu, Xi’an, Hohhot, Wuhan, Canton, Shanghai, and Harbin cities in China in November and December 2005. The survey included 20,987 children aged 5–12 years and they and their caregivers completed questionnaires. Height and weight were measured by school teachers trained in healthcare. According to the WHO child growth standards, obesity was defined as a body mass index >95
th
percentile of peers with the same age and gender. NE was defined as bed wetting for more than twice a week for 3 consecutive months. Demographic variables were compared among different groups. The prevalence of obesity, asthma, attention-deficit/hyperactivity disorder (ADHD), depressive moods, and snoring were different between the NE and without-NE groups (P < 0.05). The raw odds ratio (OR) for NE and obesity was 1.36 (95%CI = 1.07–1.74; P = 0.013) and the adjusted OR was 1.42 (95%CI = 1.11–1.82; P = 0.005) in the multivariable analysis. When adjusting for co-occurring conditions, the results showed that asthma did not affect the risk of NE (OR = 1.42, 95%CI = 1.11–1.82; P = 0.005), but ADHD (OR = 1.41; 95%CI = 1.10–1.81; P = 0.006) and depressive moods (OR = 1.34; 95%CI = 1.07–1.76; P = 0.012) slightly weakens the association between NE in children and obesity, while snoring weakens the association between obesity and NE and the risk became non-significant (OR = 1.21; 95%CI = 0.94–1.56; P = 0.138). In conclusion, obese children were at a higher risk of incurring NE compared to non-obese children. This association was weaker in children who either snored, had ADHD, or had depressive mood.</description><subject>692/699</subject><subject>692/700</subject><subject>Apnea</subject><subject>Asthma</subject><subject>Attention deficit hyperactivity disorder</subject><subject>Body mass index</subject><subject>Child</subject><subject>Children</subject><subject>China - epidemiology</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Enuresis</subject><subject>Epidemiology</subject><subject>Female</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Hyperactivity</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Mental depression</subject><subject>Mood</subject><subject>multidisciplinary</subject><subject>Multivariate Analysis</subject><subject>Nocturnal</subject><subject>Nocturnal Enuresis - complications</subject><subject>Nocturnal Enuresis - epidemiology</subject><subject>Nocturnal Enuresis - pathology</subject><subject>Obesity</subject><subject>Obesity - complications</subject><subject>Risk Factors</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Severity of Illness Index</subject><subject>Sleep</subject><subject>Sleep disorders</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><recordid>eNp9kcFO3DAQhq2KqqAtL8ChstQLl9B4bCdOD5XQqqWVEFzgbDnxZNcosbd2AuLt8bJAKQd8GFuab37PzE_IEStPWMnVtySYbFRRsqYQQnIo5AdyAKWQBXCAvVfvfXKY0k2Zj4RGsOYT2eeMKagFHJCri9BNc_RmoOjniMkl6jwNLSak3doNNqL_Tg31ZnLBF3fOIsVNjqMLQ1i5Llemabb3tI9hpMu18-Yz-dibIeHh070g179-Xi1_F-eXZ3-Wp-dFJwGmQooGRC9Ya1puWWVVg7a3SmHNBIe2r0yNFlApJQ1a2Va86pS1UrUlQmORL8iPne5mbke0HfopmkFvohtNvNfBOP1_xru1XoVbXUlZZ9UscPwkEMPfGdOkR5c6HAbjMcxJAwhZ1UrkjS_I1zfoTXjc25bitaoYlCpTsKO6GFKK2L80w0q99U3vfNPZN_3om9528eX1GC8lzy5lgO-AlFN-hfHf3-_IPgC5eKSb</recordid><startdate>20190610</startdate><enddate>20190610</enddate><creator>Zhang, Anyi</creator><creator>Li, Shenghui</creator><creator>Zhang, Yiwen</creator><creator>Jiang, Fan</creator><creator>Jin, Xingming</creator><creator>Ma, Jun</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20190610</creationdate><title>Nocturnal enuresis in obese children: a nation-wide epidemiological study from China</title><author>Zhang, Anyi ; Li, Shenghui ; Zhang, Yiwen ; Jiang, Fan ; Jin, Xingming ; Ma, Jun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-54924f41bab3d16d89edfd88e71432bf6a7ed2e8885aed5b636c8dd58b0e29de3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>692/699</topic><topic>692/700</topic><topic>Apnea</topic><topic>Asthma</topic><topic>Attention deficit hyperactivity disorder</topic><topic>Body mass index</topic><topic>Child</topic><topic>Children</topic><topic>China - 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Anyi</au><au>Li, Shenghui</au><au>Zhang, Yiwen</au><au>Jiang, Fan</au><au>Jin, Xingming</au><au>Ma, Jun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nocturnal enuresis in obese children: a nation-wide epidemiological study from China</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2019-06-10</date><risdate>2019</risdate><volume>9</volume><issue>1</issue><spage>8414</spage><pages>8414-</pages><artnum>8414</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>Childhood obesity increases the risk of obstructive sleep apnea syndrome, type 2 diabetes mellitus, cardiovascular abnormalities, and psychological and behavioral disorders. But it is unclear whether obesity is associated with childhood nocturnal enuresis (NE). This study aimed to assess the relationship between childhood obesity and NE in a nationally representative large sample in China. Subjects were enrolled from Urumqi, Chengdu, Xi’an, Hohhot, Wuhan, Canton, Shanghai, and Harbin cities in China in November and December 2005. The survey included 20,987 children aged 5–12 years and they and their caregivers completed questionnaires. Height and weight were measured by school teachers trained in healthcare. According to the WHO child growth standards, obesity was defined as a body mass index >95
th
percentile of peers with the same age and gender. NE was defined as bed wetting for more than twice a week for 3 consecutive months. Demographic variables were compared among different groups. The prevalence of obesity, asthma, attention-deficit/hyperactivity disorder (ADHD), depressive moods, and snoring were different between the NE and without-NE groups (P < 0.05). The raw odds ratio (OR) for NE and obesity was 1.36 (95%CI = 1.07–1.74; P = 0.013) and the adjusted OR was 1.42 (95%CI = 1.11–1.82; P = 0.005) in the multivariable analysis. When adjusting for co-occurring conditions, the results showed that asthma did not affect the risk of NE (OR = 1.42, 95%CI = 1.11–1.82; P = 0.005), but ADHD (OR = 1.41; 95%CI = 1.10–1.81; P = 0.006) and depressive moods (OR = 1.34; 95%CI = 1.07–1.76; P = 0.012) slightly weakens the association between NE in children and obesity, while snoring weakens the association between obesity and NE and the risk became non-significant (OR = 1.21; 95%CI = 0.94–1.56; P = 0.138). In conclusion, obese children were at a higher risk of incurring NE compared to non-obese children. This association was weaker in children who either snored, had ADHD, or had depressive mood.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>31182742</pmid><doi>10.1038/s41598-019-44532-5</doi><oa>free_for_read</oa></addata></record> |
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subjects | 692/699 692/700 Apnea Asthma Attention deficit hyperactivity disorder Body mass index Child Children China - epidemiology Diabetes mellitus Diabetes mellitus (non-insulin dependent) Enuresis Epidemiology Female Humanities and Social Sciences Humans Hyperactivity Logistic Models Male Mental depression Mood multidisciplinary Multivariate Analysis Nocturnal Nocturnal Enuresis - complications Nocturnal Enuresis - epidemiology Nocturnal Enuresis - pathology Obesity Obesity - complications Risk Factors Science Science (multidisciplinary) Severity of Illness Index Sleep Sleep disorders |
title | Nocturnal enuresis in obese children: a nation-wide epidemiological study from China |
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