Dietary Flaxseed as a Strategy for Improving Human Health

Flaxseed is a rich source of the omega-3 fatty acid, alpha linolenic acid, the lignan secoisolariciresinol diglucoside and fiber. These compounds provide bioactivity of value to the health of animals and humans through their anti-inflammatory action, anti-oxidative capacity and lipid modulating prop...

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Bibliographic Details
Published in:Nutrients 2019-05, Vol.11 (5), p.1171
Main Authors: Parikh, Mihir, Maddaford, Thane G, Austria, J Alejandro, Aliani, Michel, Netticadan, Thomas, Pierce, Grant N
Format: Article
Language:English
Subjects:
alpha-Linolenic Acid - pharmacology
alpha-Linolenic Acid - therapeutic use
animal health
Animals
anti-inflammatory activity
Anti-Inflammatory Agents - pharmacology
Anti-Inflammatory Agents - therapeutic use
antioxidant activity
Antioxidants - pharmacology
Antioxidants - therapeutic use
bioactive compounds
brain
Brain - drug effects
Butylene Glycols - pharmacology
Butylene Glycols - therapeutic use
cardiovascular diseases
Cardiovascular Diseases - therapy
Clinical trials
Diet
Dietary Fiber - pharmacology
Dietary Fiber - therapeutic use
Dietary Supplements
Fatty Acids, Omega-3 - pharmacology
Fatty Acids, Omega-3 - therapeutic use
Female
Flax - chemistry
Functional Food
Gastrointestinal Diseases - therapy
Glucosides - pharmacology
Glucosides - therapeutic use
Hormones - metabolism
human health
Humans
lignans
Lignans - pharmacology
Lignans - therapeutic use
linolenic acid
linseed
Lipid Metabolism - drug effects
menopause
neoplasms
Neoplasms - therapy
omega-3 fatty acids
Review
Seeds - chemistry
women
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Summary:Flaxseed is a rich source of the omega-3 fatty acid, alpha linolenic acid, the lignan secoisolariciresinol diglucoside and fiber. These compounds provide bioactivity of value to the health of animals and humans through their anti-inflammatory action, anti-oxidative capacity and lipid modulating properties. The characteristics of ingesting flaxseed or its bioactive components are discussed in this article. The benefits of administering flaxseed or the individual bioactive components on health and disease are also discussed in this review. Specifically, the current evidence on the benefits or limitations of dietary flaxseed in a variety of cardiovascular diseases, cancer, gastro-intestinal health and brain development and function, as well as hormonal status in menopausal women, are comprehensive topics for discussion.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu11051171