Dynamic changes in the dendritic geometry of individual neurons visualized over periods of up to three months in the superior cervical ganglion of living mice

We describe a means of visualizing the same neuron in the superior cervical ganglion of young adult mice over intervals of up to 3 months. The dendrites of these neurons change during this interval; some branches retract, others elongate, and still others appear to form de novo. Thus, neuronal dendr...

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Bibliographic Details
Published in:The Journal of neuroscience 1986-04, Vol.6 (4), p.1051-1060
Main Authors: Purves, D, Hadley, RD, Voyvodic, JT
Format: Article
Language:English
Subjects:
Animals
Dendrites - physiology
Dendrites - ultrastructure
Ganglia, Sympathetic - growth & development
Ganglia, Sympathetic - physiology
Ganglia, Sympathetic - ultrastructure
Male
Mice
Neurons - physiology
Neurons - ultrastructure
Synapses - physiology
Synapses - ultrastructure
Time Factors
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Summary:We describe a means of visualizing the same neuron in the superior cervical ganglion of young adult mice over intervals of up to 3 months. The dendrites of these neurons change during this interval; some branches retract, others elongate, and still others appear to form de novo. Thus, neuronal dendrites in this part of the nervous system are subject to continual change beyond what is usually considered the developmental period. The remodeling of postsynaptic processes further implies that the synaptic connections made onto these cells undergo substantial rearrangement well into adulthood.
ISSN:0270-6474
1529-2401
DOI:10.1523/jneurosci.06-04-01051.1986