The CeNGEN Project: The Complete Gene Expression Map of an Entire Nervous System

Differential gene expression defines individual neuron types and determines how each contributes to circuit physiology and responds to injury and disease. The C. elegans Neuronal Gene Expression Map & Network (CeNGEN) will establish a comprehensive gene expression atlas of an entire nervous syst...

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Bibliographic Details
Published in:Neuron (Cambridge, Mass.) Mass.), 2018-08, Vol.99 (3), p.430-433
Main Authors: Hammarlund, Marc, Hobert, Oliver, Miller, David M., Sestan, Nenad
Format: Article
Language:English
Subjects:
Animals
Caenorhabditis elegans
Caenorhabditis elegans Proteins - genetics
Chromosome Mapping - methods
Chromosome Mapping - trends
Datasets
Gene expression
Gene Expression Profiling - methods
Gene Expression Profiling - trends
Investigations
Morphology
National Institute of Neurological Disorders and Stroke (U.S.) - trends
Nematodes
Nervous System
Nervous System Physiological Phenomena - genetics
Neurons
Neurosciences
Sexes
United States
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Summary:Differential gene expression defines individual neuron types and determines how each contributes to circuit physiology and responds to injury and disease. The C. elegans Neuronal Gene Expression Map & Network (CeNGEN) will establish a comprehensive gene expression atlas of an entire nervous system at single-neuron resolution. Differential gene expression determines how neurons contribute to circuit physiology and respond to injury and disease. The C. elegans Neuronal Gene Expression Map & Network (CeNGEN) will establish a high-density gene expression atlas of an entire nervous system.
ISSN:0896-6273
1097-4199
DOI:10.1016/j.neuron.2018.07.042