Isolation and structure of polyoxin N

Polyoxin N, a new active component of the polyoxins, has been isolated from the culture broth of Streptomyces piomogenus. On the basis of degradative study and spectral analysis, the structure, 1-[5′-(5″-O-carbamoyl-2″-amino-2″-deoxy-L-xylonyl)amino-5′-deoxy-D-allofuranosyl uronic acid]-3-formyl-4-h...

Full description

Saved in:
Bibliographic Details
Published in:Nucleic acids research 1978-07, Vol.1 (suppl-2), p.s327-s332
Main Authors: Uramoto, Masakazu, Uzawa, Jun, Suzuki, Saburo, Isono, Kiyoshi, Liehr, J.G., McCloskey, J.A.
Format: Article
Language:English
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Polyoxin N, a new active component of the polyoxins, has been isolated from the culture broth of Streptomyces piomogenus. On the basis of degradative study and spectral analysis, the structure, 1-[5′-(5″-O-carbamoyl-2″-amino-2″-deoxy-L-xylonyl)amino-5′-deoxy-D-allofuranosyl uronic acid]-3-formyl-4-hydroxypyrazole (1), has been proposed for this antibiotic. Unlike other polyoxins, it has a pyrazole ring system as a nucleobase.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/1.suppl_2.s327