Hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection: case report and literature review

Hemophagocytic lymphohistiocytosis (HLH) is rare and life threatening syndrome. There are only a few reported cases of HLH with GI symptoms. We describe the case of an 18 months old boy who presented with a history of fever for 40 days, abdominal distention and hepatosplenomegaly. Abdominal x-ray sh...

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Published in:Journal of surgical case reports 2019-06, Vol.2019 (6), p.rjy096
Main Authors: Bahabri, Saeed, Al Rikabi, Ammar C, Alshammari, Amjad O, Alturkestany, Sara I
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Case Report
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description Hemophagocytic lymphohistiocytosis (HLH) is rare and life threatening syndrome. There are only a few reported cases of HLH with GI symptoms. We describe the case of an 18 months old boy who presented with a history of fever for 40 days, abdominal distention and hepatosplenomegaly. Abdominal x-ray showed a pneumoperitoneum. Urgent laparotomy was done which revealed an isolated cecal perforation. The histopathological findings in the subsequent resected bowel was HLH with evidence of positive EBV Barr infection.
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title Hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection: case report and literature review
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