Glucose biosensor based on screen-printed electrode modified with silicone sol–gel conducting matrix containing carbon nanotubes

This research shows that high-performance biosensors can be produced by modification of screen-printed electrodes with enzymes and conducting hydrogel based on sol–gel matrix and single-walled carbon nanotubes. Tetraethoxysilane, dimethyldiethoxysilane and polyvinyl alcohol were used as the sol–gel...

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Bibliographic Details
Published in:3 Biotech 2019-07, Vol.9 (7), p.290-7, Article 290
Main Authors: Kamanina, O. A., Kamanin, S. S., Kharkova, A. S., Arlyapov, V. A.
Format: Article
Language:English
Subjects:
Agriculture
Bioinformatics
Biomaterials
Biosensors
Biotechnology
Blood levels
Cancer Research
Chemistry
Chemistry and Materials Science
Electrodes
Electron transfer
Glucose
Hydrogels
Nanotubes
Original
Original Article
Oxidation
Polyvinyl alcohol
Silicones
Single wall carbon nanotubes
Sol-gel processes
Stem Cells
Tetraethoxysilane
Tetraethyl orthosilicate
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Summary:This research shows that high-performance biosensors can be produced by modification of screen-printed electrodes with enzymes and conducting hydrogel based on sol–gel matrix and single-walled carbon nanotubes. Tetraethoxysilane, dimethyldiethoxysilane and polyvinyl alcohol were used as the sol–gel matrix basis. Modified SWCNT provide direct electron transfer during glucose oxidation, as confirmed by cyclic voltammetry. The developed conducting sol–gel screen-printed electrodes can determine glucose within the concentration range 0.045–1.04 mM. The developed biosensor is not only in pace with its world analogues but even exceeds them by some analytical and metrological properties. The developed conducting sol–gel biosensor was used to measure the concentration of glucose in blood. The test results differed only insignificantly from those received with the help of standard glucose meter.
ISSN:2190-572X
2190-5738
DOI:10.1007/s13205-019-1818-1