Swept-Source Optical Coherence Tomography Biometer as Screening Strategy for Macular Disease in Patients Scheduled for Cataract Surgery

• Published in: Scientific reports 2019-07, Vol.9 (1), p.9912-7, Article 9912
• Main Authors: Tognetto, Daniele, Pastore, Marco R., De Giacinto, Chiara, Merli, Riccardo, Franzon, Marco, D’Aloisio, Rossella, Belfanti, Lorenzo, Giglio, Rosa, Cirigliano, Gabriella
• Format: Article
• Language: English
• Subjects: 14; 631/1647/245/2226; 639/925/930/2735; Adult; Aged; Aged, 80 and over; Cataract - physiopathology; Cataract Extraction - methods; Cataracts; Cross-Sectional Studies; Eye; Eye surgery; Female; Humanities and Social Sciences; Humans; Macular Degeneration - diagnosis; Macular Degeneration - diagnostic imaging; Male; Mass Screening - methods; Medical imaging; Middle Aged; multidisciplinary; Retina; Science; Science (multidisciplinary); Single-Blind Method; Statistical analysis; Surgery; Tomography, Optical Coherence - methods
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-019-46243-3

The aim of this study was to assess the central macular imaging captured with an optical biometer based on full-eye-length Swept-Source OCT (SS-OCT) scan as a screening strategy for identifying macular diseases in patients scheduled for cataract surgery. 1,114 eyes of 749 consecutive patients underwent a biometrical examination with IOLMaster 700 SS-OCT technology (Carl Zeiss) and conventional Spectral-Domain OCT (SD-OCT) (Spectralis OCT, Heidelberg) device analysis on the same day. Seven examiners graded the scans individually in a full-masked mode. Twenty-five eyes were excluded for media opacities. Among the 1,089 included eyes, statistical analysis revealed a mean Kendall’s Coefficient of 0.83 (range 0.76–0.89). A logistic regression model demonstrated a highly significant correlation (p