Derivation and Validation of a Novel Risk Score to Predict Overcorrection of Severe Hyponatremia: The Severe Hyponatremia Overcorrection Risk (SHOR) Score

Osmotic demyelination syndrome is the most concerning complication of severe hyponatremia, occurring with an overly rapid rate of serum sodium correction. There are limited clinical tools to aid in identifying individuals at high risk of overcorrection with severe hyponatremia. We identified all pat...

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Bibliographic Details
Published in:Clinical journal of the American Society of Nephrology 2019-07, Vol.14 (7), p.975-982
Main Authors: Woodfine, Jason D, Sood, Manish M, MacMillan, Thomas E, Cavalcanti, Rodrigo B, van Walraven, Carl
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Female
Humans
Hyponatremia - blood
Hyponatremia - drug therapy
Male
Middle Aged
Original
Sodium - blood
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Summary:Osmotic demyelination syndrome is the most concerning complication of severe hyponatremia, occurring with an overly rapid rate of serum sodium correction. There are limited clinical tools to aid in identifying individuals at high risk of overcorrection with severe hyponatremia. We identified all patients who presented to a tertiary-care hospital emergency department in Ottawa, Canada (catchment area 1.2 million) between January 1, 2003 and December 31, 2015, with serum sodium (corrected for glucose levels)
ISSN:1555-9041
1555-905X
DOI:10.2215/CJN.12251018