Sociodemographic variation in the oral microbiome

Variations in the oral microbiome are potentially implicated in social inequalities in oral disease, cancers, and metabolic disease. We describe sociodemographic variation of oral microbiomes in a diverse sample. We performed 16S rRNA sequencing on mouthwash specimens in a subsample (n = 282) of the...

Full description

Saved in:
Bibliographic Details
Published in:Annals of epidemiology 2019-07, Vol.35, p.73-80.e2
Main Authors: Renson, Audrey, Jones, Heidi E., Beghini, Francesco, Segata, Nicola, Zolnik, Christine P., Usyk, Mykhaylo, Moody, Thomas U., Thorpe, Lorna, Burk, Robert, Waldron, Levi, Dowd, Jennifer B.
Format: Article
Language:English
Subjects:
Bacteria - classification
Demographics
DNA, Bacterial - analysis
DNA, Ribosomal - genetics
DNA, Ribosomal - isolation & purification
Female
Health disparities
Health Status Disparities
Humans
Male
Microbiota - genetics
Mouth - microbiology
Mouth Mucosa - microbiology
Mouthwashes
Oral microbiome
Population Surveillance - methods
RNA, Ribosomal, 16S - genetics
RNA, Ribosomal, 16S - isolation & purification
Social epidemiology
Socioeconomic Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Variations in the oral microbiome are potentially implicated in social inequalities in oral disease, cancers, and metabolic disease. We describe sociodemographic variation of oral microbiomes in a diverse sample. We performed 16S rRNA sequencing on mouthwash specimens in a subsample (n = 282) of the 2013–2014 population-based New York City Health and Nutrition Examination Study. We examined differential abundance of 216 operational taxonomic units, and alpha and beta diversity by age, sex, income, education, nativity, and race/ethnicity. For comparison, we examined differential abundance by diet, smoking status, and oral health behaviors. Sixty-nine operational taxonomic units were differentially abundant by any sociodemographic variable (false discovery rate 
ISSN:1047-2797
1873-2585
DOI:10.1016/j.annepidem.2019.03.006