Intensive blood pressure control is associated with improved patient and graft survival after renal transplantation

Based on data of the SPRINT trial, American hypertension guidelines recently reduced the blood pressure goal from 140/90 mmHg to 130/80 mmHg for subjects with chronic kidney disease (CKD), whereas European guidelines recommend a systolic blood pressure (SBP) of 130–139 mmHg. The present analysis inv...

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Bibliographic Details
Published in:Scientific reports 2019-07, Vol.9 (1), p.10507-7, Article 10507
Main Authors: Pagonas, Nikolaos, Bauer, Frederic, Seibert, Felix S., Seidel, Maximilian, Schenker, Peter, Kykalos, Stylianos, Dürr, Michael, Reinke, Petra, Babel, Nina, Viebahn, Richard, Westhoff, Timm H.
Format: Article
Language:English
Subjects:
692/4022
692/4022/1585/104
Adolescent
Adult
Aged
Antihypertensive Agents - therapeutic use
Blood Pressure
Comorbidity
Coronary Disease - epidemiology
Diabetes Mellitus - epidemiology
Epidermal growth factor receptors
Female
Follow-Up Studies
Germany - epidemiology
Graft Survival
Health risk assessment
Humanities and Social Sciences
Humans
Hyperlipidemias - epidemiology
Hypertension
Hypertension - drug therapy
Hypertension - epidemiology
Hypertension - physiopathology
Immunosuppressive Agents - therapeutic use
Kaplan-Meier Estimate
Kidney diseases
Kidney Failure, Chronic - epidemiology
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - surgery
Kidney transplantation
Kidney Transplantation - mortality
Male
Middle Aged
multidisciplinary
Proportional Hazards Models
Recurrence
Regression analysis
Retrospective Studies
Science
Science (multidisciplinary)
Survival
Tissue Donors
Transplants & implants
Treatment Outcome
Young Adult
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Summary:Based on data of the SPRINT trial, American hypertension guidelines recently reduced the blood pressure goal from 140/90 mmHg to 130/80 mmHg for subjects with chronic kidney disease (CKD), whereas European guidelines recommend a systolic blood pressure (SBP) of 130–139 mmHg. The present analysis investigates whether a SBP 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-46991-2