The colon and terminal ileum in patients with ankylosing spondylitis and controls in Bangladesh: a macroscopic and microscopic study

Abstract Objective Little is known about gut lesions in AS patients in a developing country, such as Bangladesh. Methods Full colonoscopy, including the terminal ileum, was performed in 60 AS patients and 20 controls, without diarrhoea, to study macroscopic and microscopic lesions. Results In the co...

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Published in:Rheumatology advances in practice 2018-01, Vol.2 (2), p.rky016
Main Authors: Ferdous, Nira, Islam, Md Nazrul, Ishaque, Shamsuddin Mohammed, Akhter, Shabnam, Kamal, Mohammed, Rasker, Johannes J
Format: Article
Language:English
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Summary:Abstract Objective Little is known about gut lesions in AS patients in a developing country, such as Bangladesh. Methods Full colonoscopy, including the terminal ileum, was performed in 60 AS patients and 20 controls, without diarrhoea, to study macroscopic and microscopic lesions. Results In the colon, in 60 AS patients 17 macroscopic lesions were found, of which 11 were in the rectum; only one lesion was found in 20 controls. The prevalence of microscopic lesions in the ascending colon, sigmoid colon and rectum was 51, 44 and 50 in patients, respectively, and 13, 9 and 8 in controls. In the terminal ileum, macroscopic and microscopic lesions were seen in 21/56 and 43/56 AS patients, respectively, and in 1/20 and 9/20 controls. In the AS group, macroscopic (38.5 vs 5%, P 
ISSN:2514-1775
2514-1775
DOI:10.1093/rap/rky016