Ratio of Right to Left Ventricular Ejection: A Pilot Study Using Doppler to Detect Interventricular Dyssynchrony

• Published in: Clinical cardiology (Mahwah, N.J.) N.J.), 2011-06, Vol.34 (6), p.366-371
• Main Authors: López‐Candales, Angel, Edelman, Kathy
• Format: Article
• Language: English
• Subjects: Biological and medical sciences; Blood Pressure; Cardiology. Vascular system; Cardiovascular system; Clinical Investigation; Clinical Investigations; Echocardiography, Doppler, Pulsed; Humans; Hypertension, Pulmonary - complications; Hypertension, Pulmonary - diagnostic imaging; Hypertension, Pulmonary - physiopathology; Investigative techniques, diagnostic techniques (general aspects); Medical sciences; Middle Aged; Observer Variation; Pennsylvania; Pilot Projects; Predictive Value of Tests; Pulmonary Artery - physiopathology; Reproducibility of Results; Stroke Volume; Time Factors; Ultrasonic investigative techniques; Ventricular Dysfunction, Right - diagnostic imaging; Ventricular Dysfunction, Right - etiology; Ventricular Dysfunction, Right - physiopathology; Ventricular Function, Left; Ventricular Function, Right
• ISSN: 0160-9289; 1932-8737
• DOI: 10.1002/clc.20889

Background: Chronic pulmonary hypertension (cPH) is known to delay maximal right ventricular (RV) deformation, causing mechanical dyssynchrony, which previously has been identified only through the use of myocardial tissue Doppler imaging. However, alterations between RV and left ventricular (LV) ejection should be easily identified during routine echocardiographic examinations. Hypothesis: We hypothesized that assessment of differences in ejection fraction between left and right ventricles would be detected using pulsed Doppler. Methods: Standard echo and Doppler data were collected from 30 patients without PH (mean age, 53 ± 7 y; mean pulmonary artery systolic pressure [PASP], 31 ± 5 mm Hg) and from 40 patients with cPH (mean age, 53 ± 13 y, P not significant; mean PASP, 82 ± 24 mm Hg, P