Appropriate Therapy But Not Inappropriate Shocks Predict Survival in Implantable Cardioverter Defibrillator Patients

Background: Inappropriate implantable cardioverter defibrillator (ICD) shocks have been linked to a worse clinical outcome due to direct myocardial injury. Hypothesis: The occurrence of ventricular tachyarrhythmia indicating progression of the underlying heart disease, but not the ICD shock itself,...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2011-07, Vol.34 (7), p.433-436
Main Authors: Dichtl, Wolfgang, Wolber, Thomas, Paoli, Ursula, Brüllmann, Simon, Stühlinger, Markus, Berger, Thomas, Spuller, Karin, Strasak, Alexander, Pachinger, Otmar, Haegeli, Laurent M., Duru, Firat, Hintringer, Florian
Format: Article
Language:English
Subjects:
Aged
Austria
Biological and medical sciences
Cardiology. Vascular system
Clinical Investigation
Clinical Investigations
Death, Sudden, Cardiac - etiology
Death, Sudden, Cardiac - prevention & control
Defibrillators, Implantable - adverse effects
Disease Progression
Electric Countershock - adverse effects
Electric Countershock - instrumentation
Electric Countershock - mortality
Equipment Failure
Female
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Retrospective Studies
Risk Assessment
Risk Factors
Survival Rate
Switzerland
Tachycardia, Ventricular - complications
Tachycardia, Ventricular - mortality
Tachycardia, Ventricular - physiopathology
Tachycardia, Ventricular - therapy
Time Factors
Treatment Outcome
Ventricular Fibrillation - complications
Ventricular Fibrillation - mortality
Ventricular Fibrillation - physiopathology
Ventricular Fibrillation - therapy
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Summary:Background: Inappropriate implantable cardioverter defibrillator (ICD) shocks have been linked to a worse clinical outcome due to direct myocardial injury. Hypothesis: The occurrence of ventricular tachyarrhythmia indicating progression of the underlying heart disease, but not the ICD shock itself, has prognostic impact in clinical routine. Methods: In a retrospective study, 1117 recipients of an ICD were analyzed with respect to appropriate and inappropriate therapies and survival. Results: During a mean follow‐up of 2.92 years, appropriate therapy occurred in 27.7% and 54.0% of patients who had received an ICD for primary and secondary prevention of sudden cardiac death (SCD), respectively (P
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.20910