Influence of ferritin levels and inflammatory markers on HbA1c in the Type 2 Diabetes mellitus patients

Diabetes Mellitus (DM) is a significant public health issue worldwide due to the associated comorbidities. Recent studies have demonstrated a strong relationship between blood glucose levels and serum ferritin levels in patients with type 2 DM. The aim of the study was to investigate the association...

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Bibliographic Details
Published in:Pakistan journal of medical sciences 2019-08, Vol.35 (4), p.1030-1035
Main Author: Son, Nazan Erenoglu
Format: Article
Language:English
Subjects:
Blood
C-reactive protein
Cardiovascular disease
Care and treatment
Cholesterol
Comorbidity
Diabetes
Diabetes mellitus
Ferritin
Glucose
Glycosylated hemoglobin
Hemoglobin
Hemoglobins
Hospitals
Hyperglycemia
Insulin resistance
Medical diagnosis
Metabolism
Mortality
Original
Statistical analysis
Studies
Type 2 diabetes
Uric acid
Variance analysis
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Summary:Diabetes Mellitus (DM) is a significant public health issue worldwide due to the associated comorbidities. Recent studies have demonstrated a strong relationship between blood glucose levels and serum ferritin levels in patients with type 2 DM. The aim of the study was to investigate the association between Ferritin Levels and Inflammatory Markers on HbA1c in the Type 2 Diabetes Mellitus Patients. This single-center, cross-sectional, controlled study included patients who were admitted to the Endocrine and Metabolic Disorders outpatient clinics of the Private Kütahya Hospital in the province of Kutahya in the Western Turkey. The study included a total of 172 patients, 84 of whom had type 2 DM and 88 without diabetes and constituted the control group. A total of 190 patients with DM were admitted to the Adult Endocrine and Metabolic Diseases Outpatient Clinics of the hospital between July 1, 2018 and September 1, 2018, and among these, the study was conducted on 172 volunteer patients who met the study inclusion criteria and who did not have any missing data. The HbA1c levels, serum ferritin, hemoglobin (Hb), insulin, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), C-Reactive Protein (CRP), lipid profiles, and uric acid levels were compared between the groups. The serum ferritin levels of the patients with type 2 DM significantly increased with increasing HbA1c levels (p
ISSN:1682-024X
1681-715X
DOI:10.12669/pjms.35.4.1003