Multiple Myeloma in an Agricultural Worker Exposed to Pesticides

Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2019-05, Vol.11 (5), p.e4762
Main Authors: Packard, Elizabeth, Shahid, Zainab, Groff, Andrew, Patel, Ravi, Jain, Rohit
Format: Article
Language:English
Subjects:
Abdomen
Anemia
Back pain
Bans
Bone marrow
Cancer therapies
Case reports
Chemotherapy
Environmental Health
Family medical history
Fungicides
Health risk assessment
Herbicides
Immunoglobulins
Insecticides
Internal Medicine
Medical prognosis
Multiple myeloma
Oncology
Pathogenesis
Patients
Pesticides
Plasma
Proteins
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Summary:Multiple myeloma (MM) is a neoplastic disorder characterized by the monoclonal proliferation of plasma cells in the bone marrow. It is estimated to account for only 1% of neoplastic diseases, and there is still a great deal of uncertainty about its precise etiology. Common risk factors with a proven association with MM include ionizing radiation exposure, age greater than 65, male gender, and the presence of monoclonal gammopathy of unknown significance (MGUS).More recently, research has shown that occupational exposures to pesticides also have a significant association with the development of MM. We present the case of an adult male who presented with rib pain, back pain, fevers, and progressive shortness of breath and was ultimately found to have multiple myeloma thought to be associated with occupational exposure to the pesticide captan.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.4762