Loading…
Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators
Highlights • Migraine facial allodynia was modeled in male rats by supradural “inflammatory soup” • Proinflammatory mRNAs increased in trigeminal n. caudalis as a result. • Facial allodynia was prevented by 3 chemically diverse glial modulatory drugs.
Saved in:
| Published in: | Brain research 2017-06, Vol.1664, p.87-94 |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213 |
| container_end_page | 94 |
| container_issue | |
| container_start_page | 87 |
| container_title | Brain research |
| container_volume | 1664 |
| creator | Wieseler, Julie Ellis, Amanda McFadden, Andrew Stone, Kendra Brown, Kimberley Cady, Sara Bastos, Leandro F Sprunger, David Rezvani, Niloofar Johnson, Kirk Rice, Kenner C Maier, Steven F Watkins, Linda R |
| description | Highlights • Migraine facial allodynia was modeled in male rats by supradural “inflammatory soup” • Proinflammatory mRNAs increased in trigeminal n. caudalis as a result. • Facial allodynia was prevented by 3 chemically diverse glial modulatory drugs. |
| doi_str_mv | 10.1016/j.brainres.2017.03.011 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668623</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0006899317301191</els_id><sourcerecordid>1879665472</sourcerecordid><originalsourceid>FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213</originalsourceid><addsrcrecordid>eNqFUk1v1DAQjRCILoW_UPnIZYM_Nk58qUAVX1IlDoWzNXHGrXcde7GTrXLmj-PVthVw4WR53pv37HlTVReM1owy-W5b9wlcSJhrTllbU1FTxp5VK9a1fC35hj6vVpRSue6UEmfVq5y35SqEoi-rM94JztuGrqpfN_M-wTAn8MQF62EcYYppITnO-1IhcA87JBAGYhOiX8gYDy7ckgRTLvgwG8zEgnFFALyPwxIckOkOJuIy6X00OxxIv5D9PMHkDkjcOM4Bi84w-6NXfl29sOAzvnk4z6sfnz5-v_qyvv72-evVh-u1abic1l2n7MZa1faNUlaVmmit7BsqJOUNE41oG8FRMG4VIO9h03cAloPd9AVg4ry6POnu537EwWCYyrf1PrkR0qIjOP03Etydvo0HLaXsJBdF4O2DQIo_Z8yTHl026D0EjHPWZfZKymbT8kKVJ6pJMeeE9smGUX1MUG_1Y4L6mKCmQpcES-PFn498anuMrBDenwhYRnVwmHQ2DoPBwSU0kx6i-7_H5T8SxrvgDPgdLpi3cU6hBKGZzlxTfXPco-MasVaUdsXEb9BwyOk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1879665472</pqid></control><display><type>article</type><title>Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators</title><source>ScienceDirect Freedom Collection</source><creator>Wieseler, Julie ; Ellis, Amanda ; McFadden, Andrew ; Stone, Kendra ; Brown, Kimberley ; Cady, Sara ; Bastos, Leandro F ; Sprunger, David ; Rezvani, Niloofar ; Johnson, Kirk ; Rice, Kenner C ; Maier, Steven F ; Watkins, Linda R</creator><creatorcontrib>Wieseler, Julie ; Ellis, Amanda ; McFadden, Andrew ; Stone, Kendra ; Brown, Kimberley ; Cady, Sara ; Bastos, Leandro F ; Sprunger, David ; Rezvani, Niloofar ; Johnson, Kirk ; Rice, Kenner C ; Maier, Steven F ; Watkins, Linda R</creatorcontrib><description>Highlights • Migraine facial allodynia was modeled in male rats by supradural “inflammatory soup” • Proinflammatory mRNAs increased in trigeminal n. caudalis as a result. • Facial allodynia was prevented by 3 chemically diverse glial modulatory drugs.</description><identifier>ISSN: 0006-8993</identifier><identifier>EISSN: 1872-6240</identifier><identifier>DOI: 10.1016/j.brainres.2017.03.011</identifier><identifier>PMID: 28322750</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Dura ; Dura Mater - drug effects ; Encephalitis - complications ; Encephalitis - immunology ; Headache ; Hyperalgesia - chemically induced ; Hyperalgesia - complications ; Hyperalgesia - immunology ; Hyperalgesia - prevention & control ; Inflammation Mediators - metabolism ; Interleukin-1 ; Macrophages - immunology ; Macrophages - metabolism ; Male ; Microglia - immunology ; Microglia - metabolism ; Migraine ; Migraine Disorders - complications ; Minocycline - administration & dosage ; Neurology ; OX42 ; Pyridines - administration & dosage ; Rats, Sprague-Dawley ; Trigeminal Caudal Nucleus - drug effects ; Trigeminal Caudal Nucleus - immunology ; Tumor necrosis factor alpha</subject><ispartof>Brain research, 2017-06, Vol.1664, p.87-94</ispartof><rights>2017 Elsevier B.V.</rights><rights>Copyright © 2017 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213</citedby><cites>FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28322750$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wieseler, Julie</creatorcontrib><creatorcontrib>Ellis, Amanda</creatorcontrib><creatorcontrib>McFadden, Andrew</creatorcontrib><creatorcontrib>Stone, Kendra</creatorcontrib><creatorcontrib>Brown, Kimberley</creatorcontrib><creatorcontrib>Cady, Sara</creatorcontrib><creatorcontrib>Bastos, Leandro F</creatorcontrib><creatorcontrib>Sprunger, David</creatorcontrib><creatorcontrib>Rezvani, Niloofar</creatorcontrib><creatorcontrib>Johnson, Kirk</creatorcontrib><creatorcontrib>Rice, Kenner C</creatorcontrib><creatorcontrib>Maier, Steven F</creatorcontrib><creatorcontrib>Watkins, Linda R</creatorcontrib><title>Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators</title><title>Brain research</title><addtitle>Brain Res</addtitle><description>Highlights • Migraine facial allodynia was modeled in male rats by supradural “inflammatory soup” • Proinflammatory mRNAs increased in trigeminal n. caudalis as a result. • Facial allodynia was prevented by 3 chemically diverse glial modulatory drugs.</description><subject>Animals</subject><subject>Dura</subject><subject>Dura Mater - drug effects</subject><subject>Encephalitis - complications</subject><subject>Encephalitis - immunology</subject><subject>Headache</subject><subject>Hyperalgesia - chemically induced</subject><subject>Hyperalgesia - complications</subject><subject>Hyperalgesia - immunology</subject><subject>Hyperalgesia - prevention & control</subject><subject>Inflammation Mediators - metabolism</subject><subject>Interleukin-1</subject><subject>Macrophages - immunology</subject><subject>Macrophages - metabolism</subject><subject>Male</subject><subject>Microglia - immunology</subject><subject>Microglia - metabolism</subject><subject>Migraine</subject><subject>Migraine Disorders - complications</subject><subject>Minocycline - administration & dosage</subject><subject>Neurology</subject><subject>OX42</subject><subject>Pyridines - administration & dosage</subject><subject>Rats, Sprague-Dawley</subject><subject>Trigeminal Caudal Nucleus - drug effects</subject><subject>Trigeminal Caudal Nucleus - immunology</subject><subject>Tumor necrosis factor alpha</subject><issn>0006-8993</issn><issn>1872-6240</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNqFUk1v1DAQjRCILoW_UPnIZYM_Nk58qUAVX1IlDoWzNXHGrXcde7GTrXLmj-PVthVw4WR53pv37HlTVReM1owy-W5b9wlcSJhrTllbU1FTxp5VK9a1fC35hj6vVpRSue6UEmfVq5y35SqEoi-rM94JztuGrqpfN_M-wTAn8MQF62EcYYppITnO-1IhcA87JBAGYhOiX8gYDy7ckgRTLvgwG8zEgnFFALyPwxIckOkOJuIy6X00OxxIv5D9PMHkDkjcOM4Bi84w-6NXfl29sOAzvnk4z6sfnz5-v_qyvv72-evVh-u1abic1l2n7MZa1faNUlaVmmit7BsqJOUNE41oG8FRMG4VIO9h03cAloPd9AVg4ry6POnu537EwWCYyrf1PrkR0qIjOP03Etydvo0HLaXsJBdF4O2DQIo_Z8yTHl026D0EjHPWZfZKymbT8kKVJ6pJMeeE9smGUX1MUG_1Y4L6mKCmQpcES-PFn498anuMrBDenwhYRnVwmHQ2DoPBwSU0kx6i-7_H5T8SxrvgDPgdLpi3cU6hBKGZzlxTfXPco-MasVaUdsXEb9BwyOk</recordid><startdate>20170601</startdate><enddate>20170601</enddate><creator>Wieseler, Julie</creator><creator>Ellis, Amanda</creator><creator>McFadden, Andrew</creator><creator>Stone, Kendra</creator><creator>Brown, Kimberley</creator><creator>Cady, Sara</creator><creator>Bastos, Leandro F</creator><creator>Sprunger, David</creator><creator>Rezvani, Niloofar</creator><creator>Johnson, Kirk</creator><creator>Rice, Kenner C</creator><creator>Maier, Steven F</creator><creator>Watkins, Linda R</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20170601</creationdate><title>Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators</title><author>Wieseler, Julie ; Ellis, Amanda ; McFadden, Andrew ; Stone, Kendra ; Brown, Kimberley ; Cady, Sara ; Bastos, Leandro F ; Sprunger, David ; Rezvani, Niloofar ; Johnson, Kirk ; Rice, Kenner C ; Maier, Steven F ; Watkins, Linda R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Dura</topic><topic>Dura Mater - drug effects</topic><topic>Encephalitis - complications</topic><topic>Encephalitis - immunology</topic><topic>Headache</topic><topic>Hyperalgesia - chemically induced</topic><topic>Hyperalgesia - complications</topic><topic>Hyperalgesia - immunology</topic><topic>Hyperalgesia - prevention & control</topic><topic>Inflammation Mediators - metabolism</topic><topic>Interleukin-1</topic><topic>Macrophages - immunology</topic><topic>Macrophages - metabolism</topic><topic>Male</topic><topic>Microglia - immunology</topic><topic>Microglia - metabolism</topic><topic>Migraine</topic><topic>Migraine Disorders - complications</topic><topic>Minocycline - administration & dosage</topic><topic>Neurology</topic><topic>OX42</topic><topic>Pyridines - administration & dosage</topic><topic>Rats, Sprague-Dawley</topic><topic>Trigeminal Caudal Nucleus - drug effects</topic><topic>Trigeminal Caudal Nucleus - immunology</topic><topic>Tumor necrosis factor alpha</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wieseler, Julie</creatorcontrib><creatorcontrib>Ellis, Amanda</creatorcontrib><creatorcontrib>McFadden, Andrew</creatorcontrib><creatorcontrib>Stone, Kendra</creatorcontrib><creatorcontrib>Brown, Kimberley</creatorcontrib><creatorcontrib>Cady, Sara</creatorcontrib><creatorcontrib>Bastos, Leandro F</creatorcontrib><creatorcontrib>Sprunger, David</creatorcontrib><creatorcontrib>Rezvani, Niloofar</creatorcontrib><creatorcontrib>Johnson, Kirk</creatorcontrib><creatorcontrib>Rice, Kenner C</creatorcontrib><creatorcontrib>Maier, Steven F</creatorcontrib><creatorcontrib>Watkins, Linda R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Brain research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wieseler, Julie</au><au>Ellis, Amanda</au><au>McFadden, Andrew</au><au>Stone, Kendra</au><au>Brown, Kimberley</au><au>Cady, Sara</au><au>Bastos, Leandro F</au><au>Sprunger, David</au><au>Rezvani, Niloofar</au><au>Johnson, Kirk</au><au>Rice, Kenner C</au><au>Maier, Steven F</au><au>Watkins, Linda R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators</atitle><jtitle>Brain research</jtitle><addtitle>Brain Res</addtitle><date>2017-06-01</date><risdate>2017</risdate><volume>1664</volume><spage>87</spage><epage>94</epage><pages>87-94</pages><issn>0006-8993</issn><eissn>1872-6240</eissn><abstract>Highlights • Migraine facial allodynia was modeled in male rats by supradural “inflammatory soup” • Proinflammatory mRNAs increased in trigeminal n. caudalis as a result. • Facial allodynia was prevented by 3 chemically diverse glial modulatory drugs.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>28322750</pmid><doi>10.1016/j.brainres.2017.03.011</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0006-8993 |
| ispartof | Brain research, 2017-06, Vol.1664, p.87-94 |
| issn | 0006-8993 1872-6240 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6668623 |
| source | ScienceDirect Freedom Collection |
| subjects | Animals Dura Dura Mater - drug effects Encephalitis - complications Encephalitis - immunology Headache Hyperalgesia - chemically induced Hyperalgesia - complications Hyperalgesia - immunology Hyperalgesia - prevention & control Inflammation Mediators - metabolism Interleukin-1 Macrophages - immunology Macrophages - metabolism Male Microglia - immunology Microglia - metabolism Migraine Migraine Disorders - complications Minocycline - administration & dosage Neurology OX42 Pyridines - administration & dosage Rats, Sprague-Dawley Trigeminal Caudal Nucleus - drug effects Trigeminal Caudal Nucleus - immunology Tumor necrosis factor alpha |
| title | Supradural inflammatory soup in awake and freely moving rats induces facial allodynia that is blocked by putative immune modulators |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T21%3A36%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Supradural%20inflammatory%20soup%20in%20awake%20and%20freely%20moving%20rats%20induces%20facial%20allodynia%20that%20is%20blocked%20by%20putative%20immune%20modulators&rft.jtitle=Brain%20research&rft.au=Wieseler,%20Julie&rft.date=2017-06-01&rft.volume=1664&rft.spage=87&rft.epage=94&rft.pages=87-94&rft.issn=0006-8993&rft.eissn=1872-6240&rft_id=info:doi/10.1016/j.brainres.2017.03.011&rft_dat=%3Cproquest_pubme%3E1879665472%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c526t-889f4ff97b599f952637f6b503602513537532e312f9ae2ba4b8aaf2af4b53213%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1879665472&rft_id=info:pmid/28322750&rfr_iscdi=true |