Addiction and Arousal: Alternative Roles of Hypothalamic Peptides

The importance of the lateral hypothalamus in the regulation of reward and motivation has long been recognized. However, the neuronal network involved in such a hypothalamic regulation of reward remains essentially unknown. Recently, hypocretin-containing neurons, a group of hypothalamic neurons kno...

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Bibliographic Details
Published in:The Journal of neuroscience 2006-10, Vol.26 (41), p.10372-10375
Main Authors: Lecea, Luis de, Jones, Barbara E, Boutrel, Benjamin, Borgland, Stephanie L, Nishino, Seiji, Bubser, Michael, DiLeone, Ralph
Format: Article
Language:English
Subjects:
Animals
Arousal - physiology
Behavior, Addictive - metabolism
Humans
Hypothalamic Area, Lateral - metabolism
Hypothalamus - metabolism
Neuropeptides - metabolism
Symposia and Mini-Symposia
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Summary:The importance of the lateral hypothalamus in the regulation of reward and motivation has long been recognized. However, the neuronal network involved in such a hypothalamic regulation of reward remains essentially unknown. Recently, hypocretin-containing neurons, a group of hypothalamic neurons known to be associated with the stability of arousal, have emerged as important structures in the control of brain reward function. This review summarizes a Mini-Symposium presented at the 2006 Annual Meeting of the Society for Neuroscience.
ISSN:0270-6474
1529-2401
DOI:10.1523/JNEUROSCI.3118-06.2006