Left ventricular ejection time is an independent predictor of incident heart failure in a community‐based cohort

Aims Systolic time intervals change in the progress of cardiac dysfunction. The usefulness of left ventricular ejection time (LVET) to predict cardiovascular morbidity, however, is unknown. Methods and results We studied middle‐aged African‐Americans from one of four cohorts of the Atherosclerosis R...

Full description

Saved in:
Bibliographic Details
Published in:European journal of heart failure 2018-07, Vol.20 (7), p.1106-1114
Main Authors: Biering‐Sørensen, Tor, Querejeta Roca, Gabriela, Hegde, Sheila M., Shah, Amil M., Claggett, Brian, Mosley, Thomas H., Butler, Kenneth R., Solomon, Scott D.
Format: Article
Language:English
Subjects:
Echocardiography
General population
Incident heart failure
Outcome
Systolic ejection time
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aims Systolic time intervals change in the progress of cardiac dysfunction. The usefulness of left ventricular ejection time (LVET) to predict cardiovascular morbidity, however, is unknown. Methods and results We studied middle‐aged African‐Americans from one of four cohorts of the Atherosclerosis Risk in Communities study (Jackson cohort, n=1980) who underwent echocardiography between 1993 and 1995. Left ventricular ejection time was measured by pulsed‐wave Doppler of the left ventricular outflow tract and related to outcomes. A shorter LVET was associated with younger age, male sex, higher diastolic blood pressure, higher proportion of diabetes, higher heart rate, higher blood glucose levels and worse fractional shortening. During a median follow‐up of 17.6 years, 384 (19%) had incident heart failure (HF), 158 (8%) had a myocardial infarction, and 587 (30%) died. In univariable analysis, a lower LVET was significantly associated with increased risk of all events (P
ISSN:1388-9842
1879-0844
DOI:10.1002/ejhf.928