Engaging African American Men as Citizen Scientists to Validate a Prostate Cancer Biomarker: Work-in-Progress

• Published in: Progress in community health partnerships 2019, Vol.13 (5), p.103-112
• Main Authors: Watson, Karriem S, Henderson, Vida, Murray, Marcus, Murphy, Adam B, Levi, Josef Ben, McDowell, Tiffany, Holloway-Beth, Alfreda, Gogana, Pooja, Dixon, Michael A, Moore, LeAndre, Hall, Ivanhoe, Kimbrough, Alexander, Molina, Yamilé, Winn, Robert A
• Format: Article
• Language: English
• Subjects: Adult; Age Factors; Black or African American; Community Participation; Community-Based Participatory Research - organization & administration; Early Detection of Cancer - methods; Humans; Male; Middle Aged; Motivation; Patient Selection; Prostate-Specific Antigen - blood; Prostatic Neoplasms - diagnosis; Social Networking; Socioeconomic Factors
• ISSN: 1557-0541; 1557-055X; 1557-055X
• DOI: 10.1353/cpr.2019.0043

African American men (AAM) are under-represented in prostate cancer (PCa) research despite known disparities. Screening with prostate-specific antigen (PSA) has low specificity for high-grade PCa leading to PCa over diagnosis. The Prostate Health Index (PHI) has higher specificity for lethal PCa but needs validation in AAM. Engaging AAM as citizen scientists (CSs) may improve participation of AAM in PCa research.Results and Lessons Learned: Eight CSs completed all training modules and 139 AAM were recruited. Challenges included equity in research leadership among multiple principal investigators (PIs) and coordinating CSs trainings. Engaging AAM CSs can support engaging/recruiting AAM in PCa biomarker validation research. Equity among multiple stakeholders can be challenging, but proves beneficial in engaging AAM in research. Assess feasibility of mobilizing CSs to recruit AAM as controls for PHI PCa validation biomarker study. We highlight social networks/assets of stakeholders, CSs curriculum development/implementation, and recruitment of healthy controls for PHI validation.