Update on the global epidemiology of intussusception: a systematic review of incidence rates, age distributions and case-fatality ratios among children aged <5 years, before the introduction of rotavirus vaccination

Abstract Background In some countries that have introduced oral rotavirus vaccines, a small but elevated risk of intussusception—a rare bowel disorder—has been reported. Updated estimates on the global epidemiology of intussusception are needed to help predict the potential number of intussusception...

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Bibliographic Details
Published in:International journal of epidemiology 2019-08, Vol.48 (4), p.1316-1326
Main Authors: Clark, Andrew D, Hasso-Agopsowicz, Mateusz, Kraus, Matthew W, Stockdale, Lisa K, Sanderson, Colin F B, Parashar, Umesh D, Tate, Jacqueline E
Format: Article
Language:English
Subjects:
Age Distribution
Child, Preschool
Hospitalization
Humans
Incidence
Infant
Intussusception - epidemiology
Intussusception - etiology
Intussusception - mortality
Miscellaneous
Rotavirus Infections - prevention & control
Rotavirus Vaccines - adverse effects
Vaccination - methods
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Summary:Abstract Background In some countries that have introduced oral rotavirus vaccines, a small but elevated risk of intussusception—a rare bowel disorder—has been reported. Updated estimates on the global epidemiology of intussusception are needed to help predict the potential number of intussusception cases that could be caused by the vaccine in different settings. Methods We estimated incidence rates, age distributions and case-fatality ratios (CFRs) for intussusception hospital admissions among children aged
ISSN:0300-5771
1464-3685
DOI:10.1093/ije/dyz028