Role of adjuvant radiation or re-excision for early stage vulvar squamous cell carcinoma with positive or close surgical margins

This study aims to evaluate whether re-excision or adjuvant radiation for stage I vulvar squamous cell carcinoma (SCC) with either a close or positive surgical margin improves recurrence-free survival. Patients with pathologically confirmed FIGO stage I vulvar SCC who underwent primary surgical mana...

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Bibliographic Details
Published in:Gynecologic oncology 2019-08, Vol.154 (2), p.276-279
Main Authors: Bedell, Sabrina M., Hedberg, Chloe, Griffin, Anna, Pearson, Hannah, Wilhite, Annelise, Rubin, Nathan, Erickson, Britt K.
Format: Article
Language:English
Subjects:
Adjuvant radiation
Aged
Aged, 80 and over
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - radiotherapy
Carcinoma, Squamous Cell - surgery
Case-Control Studies
Close margins
Disease-Free Survival
Early stage
Female
Humans
Margins of Excision
Middle Aged
Neoplasm Recurrence, Local - mortality
Proportional Hazards Models
Radiotherapy, Adjuvant - methods
Re-excision
Reoperation
Retrospective Studies
Squamous cell carcinoma
Time Factors
Vulva
Vulvar Neoplasms - mortality
Vulvar Neoplasms - pathology
Vulvar Neoplasms - radiotherapy
Vulvar Neoplasms - surgery
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Summary:This study aims to evaluate whether re-excision or adjuvant radiation for stage I vulvar squamous cell carcinoma (SCC) with either a close or positive surgical margin improves recurrence-free survival. Patients with pathologically confirmed FIGO stage I vulvar SCC who underwent primary surgical management between January 1, 1995 and September 30, 2017 and had positive or close (
ISSN:0090-8258
1095-6859
DOI:10.1016/j.ygyno.2019.05.028