Nanomaterials as Promising Alternative in the Infection Treatment

Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the...

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Bibliographic Details
Published in:International journal of molecular sciences 2019-08, Vol.20 (15), p.3806
Main Authors: Vallet-Regí, María, González, Blanca, Izquierdo-Barba, Isabel
Format: Article
Language:English
Subjects:
Acidity
Adhesion
Advantages
Anti-Bacterial Agents - therapeutic use
Antibiotics
Antimicrobial agents
Bacteria
Bacteria - drug effects
Bacteria - pathogenicity
Bacterial Adhesion - drug effects
Bacterial infections
Bacterial Infections - microbiology
Bacterial Infections - therapy
Biocompatibility
Biofilms
Biofilms - drug effects
Bioglass
Bones
Cell adhesion & migration
Drug delivery
Drug delivery systems
Global marketing
Humans
Immune system
Infections
Lysine
Medical equipment
Nanomaterials
Nanoparticles
Nanostructures - therapeutic use
Nanotechnology
Osseointegration
Permeability
Physiology
Review
Toxicology
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Summary:Both the prevalence of antibiotic resistance and the increased biofilm-associated infections are boosting the demand for new advanced and more effective treatment for such infections. In this sense, nanotechnology offers a ground-breaking platform for addressing this challenge. This review shows the current progress in the field of antimicrobial inorganic-based nanomaterials and their activity against bacteria and bacterial biofilm. Herein, nanomaterials preventing the bacteria adhesion and nanomaterials treating the infection once formed are presented through a classification based on their functionality. To fight infection, nanoparticles with inherent antibacterial activity and nanoparticles acting as nanovehicles are described, emphasizing the design of the carrier nanosystems with properties targeting the bacteria and the biofilm.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms20153806