Seroprevalence and trends in transfusion transmissible infections among voluntary non-remunerated blood donors at the Malawi Blood Transfusion Service-a time trend study

Collecting blood from voluntary non-remunerated blood donors from low risk populations is a key strategy for blood safety. Identifying such populations involves analysis of population and blood donor data to identify risk factors for transfusion transmissible infections (TTIs). There are no recent s...

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Bibliographic Details
Published in:Malawi medical journal 2019-06, Vol.31 (2), p.118-125
Main Authors: M'baya, Bridon, Jumbe, Vincent, Samuel, Vincent, M'bwana, Robert, Mangani, Charles
Format: Article
Language:English
Subjects:
Adolescent
Blood & organ donations
Blood Donors - statistics & numerical data
Blood Safety
Female
Hepatitis B - diagnosis
Hepatitis B - epidemiology
Hepatitis C - diagnosis
Hepatitis C - epidemiology
HIV Infections - diagnosis
HIV Infections - epidemiology
Humans
Infections
Malawi - epidemiology
Male
Middle Aged
Original Research
Retrospective Studies
Seroepidemiologic Studies
Syphilis
Syphilis - epidemiology
Transfusion Reaction - epidemiology
Trends
Young Adult
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Summary:Collecting blood from voluntary non-remunerated blood donors from low risk populations is a key strategy for blood safety. Identifying such populations involves analysis of population and blood donor data to identify risk factors for transfusion transmissible infections (TTIs). There are no recent seroprevalence statistics for blood donors in Malawi. This study fills this gap by describing characteristics of blood donors, trend of annual prevalence of HIV, HBV, HCV and syphilis and factors associated with each TTI. Retrospective analysis of blood donors' records in the MBTS database from 2011 to 2015 was undertaken. Summary statistics were performed to describe characteristics of the blood donors. Univariable and multivariable logistic regression analyses were performed to determine association between prevalence of infections and socio-demographic factors. Time trend analysis was done to assess changes in prevalence. P-value
ISSN:1995-7262
1995-7270
1995-7262
DOI:10.4314/mmj.v31i2.3