Diagnostic radiation-induced regression of a metastatic primary intracranial germinoma: a case report

Pineal region germinomas are sensitive to radiotherapy. Standard neurosurgical management involves obtaining a tissue biopsy and to relieve the often accompanying obstructive hydrocephalus. We present a patient with a suspected hyper-radiosensitive metastatic primary intracranial germinoma where com...

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Bibliographic Details
Published in:British journal of neurosurgery 2022-04, Vol.36 (2), p.258-261
Main Authors: Woo, Peter Y M, Kakaizada, Sofia, Chan, Cherry C Y, Chan, Timothy S K, Wong, Hoi-Tung, Chan, Kwong-Yau
Format: Article
Language:English
Subjects:
Biopsy - adverse effects
Brain Neoplasms - diagnostic imaging
Brain Neoplasms - pathology
Brain Neoplasms - radiotherapy
Germinoma - diagnostic imaging
Germinoma - radiotherapy
Humans
Hydrocephalus - etiology
Pineal Gland - diagnostic imaging
Pineal Gland - pathology
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Summary:Pineal region germinomas are sensitive to radiotherapy. Standard neurosurgical management involves obtaining a tissue biopsy and to relieve the often accompanying obstructive hydrocephalus. We present a patient with a suspected hyper-radiosensitive metastatic primary intracranial germinoma where computed tomography scanning resulted in tumor regression before radiotherapy could be administered.
ISSN:0268-8697
1360-046X
DOI:10.1080/02688697.2018.1519110