Gastrointestinal motility and absorptive disorders in patients with inflammatory bowel diseases: Prevalence, diagnosis and treatment

Inflammatory bowel diseases (IBD), Crohn`s disease and ulcerative colitis, are chronic conditions associated with high morbidity and healthcare costs. The natural history of IBD is variable and marked by alternating periods of flare and remission. Even though the use of newer therapeutic targets has...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2019-08, Vol.25 (31), p.4414-4426
Main Authors: Barros, Luísa Leite, Farias, Alberto Queiroz, Rezaie, Ali
Format: Article
Language:English
Subjects:
Abdominal Pain - diagnosis
Abdominal Pain - epidemiology
Abdominal Pain - etiology
Abdominal Pain - therapy
Constipation - diagnosis
Constipation - epidemiology
Constipation - etiology
Constipation - therapy
Diarrhea - diagnosis
Diarrhea - epidemiology
Diarrhea - etiology
Diarrhea - therapy
Dyspepsia - diagnosis
Dyspepsia - epidemiology
Dyspepsia - etiology
Dyspepsia - therapy
Fecal Incontinence - diagnosis
Fecal Incontinence - epidemiology
Fecal Incontinence - etiology
Fecal Incontinence - therapy
Gastrointestinal Motility - physiology
Humans
Inflammatory Bowel Diseases - complications
Inflammatory Bowel Diseases - physiopathology
Inflammatory Bowel Diseases - therapy
Minireviews
Prevalence
Severity of Illness Index
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Summary:Inflammatory bowel diseases (IBD), Crohn`s disease and ulcerative colitis, are chronic conditions associated with high morbidity and healthcare costs. The natural history of IBD is variable and marked by alternating periods of flare and remission. Even though the use of newer therapeutic targets has been associated with higher rates of mucosal healing, a great proportion of IBD patients remain symptomatic despite effective control of inflammation. These symptoms may include but not limited to abdominal pain, dyspepsia, diarrhea, urgency, fecal incontinence, constipation or bloating. In this setting, commonly there is an overlap with gastrointestinal (GI) motility and absorptive disorders. Early recognition of these conditions greatly improves patient care and may decrease the risk of mistreatment. Therefore, in this review we describe the prevalence, diagnosis and treatment of GI motility and absorptive disorders that commonly affect patients with IBD.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v25.i31.4414