Treatment of Unruptured, Saccular, Anterior Choroidal Artery Aneurysms with Flow Diversion: A Single Centre Experience

• Published in: Clinical neuroradiology (Munich) 2019-09, Vol.29 (3), p.459-465
• Main Authors: Bhogal, P., Ganslandt, O., Bäzner, H., Henkes, H., Aguilar Perez, M.
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aspirin - administration & dosage; Cerebral Arteries - diagnostic imaging; Clopidogrel - administration & dosage; Endovascular Procedures - adverse effects; Endovascular Procedures - instrumentation; Endovascular Procedures - methods; Female; Humans; Intracranial Aneurysm - diagnostic imaging; Intracranial Aneurysm - therapy; Male; Medicine; Medicine & Public Health; Middle Aged; Neurology; Neuroradiology; Neurosurgery; Original; Original Article; Platelet Aggregation Inhibitors - administration & dosage; Postoperative Complications; Prospective Studies; Retrospective Studies; Vascular Patency
• ISSN: 1869-1439; 1869-1447
• DOI: 10.1007/s00062-018-0677-1

Background The region of the brain supplied by the anterior choroidal artery (AChoA) is exquisitely eloquent. Aneurysms arising at or close to the origin of the vessel are not uncommon and damage or occlusion to the vessel can result in devastating consequences. The optimal treatment strategy is yet to be determined. Objective We sought to determine the efficacy of flow diversion for the treatment of unruptured AChoA aneurysms. Method A retrospective review of our prospectively maintained database was performed to identify all patients with unruptured aneurysms of the AChoA between March 2009 and May 2017. The fundus size, number and type of flow-diverting stent (FD), complications and follow-up data were recorded. Results We identified 30 patients (60% female), average age 52.8 ± 10.8 years (range 27–73), with 30 aneurysms. The aneurysms were generally small with a mean fundus diameter of 3.4 mm (range 1–7 mm). Early angiographic follow-up data were available for all patients at which point 15 aneurysms were completely occluded (50%). Delayed angiographic follow-up was available in 24 patients and occlusion was seen in 21 patients (87.5%). Of the patients one developed transient ischemic symptoms after interruption of the antiplatelet medication and another patient had a small embolic infarct with transient symptoms in the periprocedural period. Conclusion Flow diversion can be used to successfully treat aneurysms of the AChoA. The treatment carries a high rate of technical and radiological success with a good safety profile.