18F-FDG Positron-Emission Tomography/Computed Tomography Findings of Radiographic Lesions Suggesting Old Healed Pulmonary Tuberculosis and High-risk Signs of Predicting Recurrence: A Retrospective Study

Pulmonary tuberculosis (PTB) is a common worldwide infection with high mortality and morbidity, especially in developing countries. This study analyzed PET/CT findings in tumor patients with radiographic lesions suggesting old healed pulmonary tuberculosis (OHPTB) and imaging follow-up to find and v...

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Bibliographic Details
Published in:Scientific reports 2019-08, Vol.9 (1), p.12582-7, Article 12582
Main Authors: Ji, Yu, Shao, Chunchun, Cui, Yong, Shao, Guangrui, Zheng, Jingsong
Format: Article
Language:English
Subjects:
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Adult
Aged
Aged, 80 and over
Computed tomography
Developing countries
Female
Fluorodeoxyglucose F18
Humanities and Social Sciences
Humans
LDCs
Lesions
Male
Middle Aged
Morbidity
multidisciplinary
Patients
Positron emission tomography
Positron Emission Tomography Computed Tomography
Prognosis
Recurrence
Retrospective Studies
Risk
Science
Science (multidisciplinary)
Tomography
Tuberculosis
Tuberculosis, Pulmonary - diagnostic imaging
Tumors
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Summary:Pulmonary tuberculosis (PTB) is a common worldwide infection with high mortality and morbidity, especially in developing countries. This study analyzed PET/CT findings in tumor patients with radiographic lesions suggesting old healed pulmonary tuberculosis (OHPTB) and imaging follow-up to find and verify PET/CT signs that may predict tuberculosis recurrence. A retrospective analysis of the tumor patients was carried out. These patients underwent 18F-FDG PET/CT in our center from 2010 to 2018. Confirmation of tuberculosis recurrence was obtained by follow-up of morphological changes in old lesions by PET/CT or CT. In total, 238 patients with a complete medical history were included in the final study, and 22 patients experienced OHPTB recurrence. We found that the SUVmax of tuberculosis in PET/CT was significantly increased in the recurrence group compared to the non-recurrence group [5.00 (3.40, 7.30) vs. 1.10 (0.80, 1.30), P 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-019-49057-5