Endoscopic optical coherence tomography enables morphological and subnanometer vibratory imaging of the porcine cochlea through the round window

A highly phase stable hand-held (HH) endoscopic system has been developed for optical coherence tomography and vibrometry. Designed to transit the ear canal to the middle ear space and peer through the round window (RW), it is capable of imaging the vibratory function of the cochlear soft tissues wi...

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Bibliographic Details
Published in:Optics letters 2018-05, Vol.43 (9), p.1966-1969
Main Authors: Kim, Wihan, Kim, Sangmin, Oghalai, John S, Applegate, Brian E
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Animals
Cochlea
Cochlea - diagnostic imaging
Ear
Endoscopes
Endoscopy
Endoscopy - methods
Imaging
Medical imaging
Middle ear
Optical Coherence Tomography
Phase stability
Round Window, Ear - diagnostic imaging
Soft tissues
Swine
Tomography
Tomography, Optical Coherence - methods
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Summary:A highly phase stable hand-held (HH) endoscopic system has been developed for optical coherence tomography and vibrometry. Designed to transit the ear canal to the middle ear space and peer through the round window (RW), it is capable of imaging the vibratory function of the cochlear soft tissues with subnanometer scale sensitivity. A side-looking, 9 cm long rigid endoscope with a distal diameter of 1.2 mm, was able to fit within the RW niche and provide imaging access. The phase stability was achieved in part by fully integrating a Michelson interferometer into the HH device. Ex vivo imaging of a domestic pig demonstrated the system's ability for functional vibratory imaging of the cochlea via the RW.
ISSN:0146-9592
1539-4794
DOI:10.1364/ol.43.001966