Diagnostic Value of Bone SPECT/CT in Patients with Suspected Osteomyelitis

The aim of our retrospective study was to evaluate the contribution of single photon emission computed tomography/computed tomography (SPECT/CT) to three phase bone scintigraphy/SPECT for the assessment of osteomyelitis (OM) and patient’s management. Eighty-five patients who were suspected as having...

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Bibliographic Details
Published in:Molecular imaging and radionuclide therapy 2019-10, Vol.28 (3), p.89-95
Main Authors: Arıcan, Pelin, Okudan, Berna, Şefizade, Rıza, Naldöken, Seniha
Format: Article
Language:English
Subjects:
Accuracy
Biomedical materials
Computation
Computed tomography
Diagnosis
Diagnostic systems
Drug dosages
Emission analysis
Infections
Laboratories
Medical diagnosis
Medical imaging
NMR
Nuclear magnetic resonance
Nuclear medicine
Original
Osteomyelitis
Patients
Photon emission
Prostheses
Scintigraphy
Single photon emission computed tomography
Systematic review
Tıp
Tomography
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Summary:The aim of our retrospective study was to evaluate the contribution of single photon emission computed tomography/computed tomography (SPECT/CT) to three phase bone scintigraphy/SPECT for the assessment of osteomyelitis (OM) and patient’s management. Eighty-five patients who were suspected as having OM were included in this study. Tc-99m MDP three phase bone scintigraphy and SPECT/CT were performed to the region of suspected OM. SPECT/CT findings were compared with the findings of planar images/SPECT. Both planar bone scan/SPECT and SPECT/CT findings were divided into two groups: With OM and without OM. In all patients, scintigraphic diagnosis was confirmed by clinical follow up, laboratory findings, microscopic-bacteriological examinations, radiological, surgical, and pathological findings. SPECT/CT changed the diagnosis and treatment planning in 14/85 (16.5%) patients. SPECT/CT was significantly superior to planar scan/SPECT imaging for determining OM (kappa value was 0.626 for planar scan/SPECT, 0.929 for SPECT/CT). SPECT/CT was statistically more successful in detection of chronic OM, and useful in differentiating chronic OM from acute OM (kappa value was 0.541 for planar scan/SPECT, 0.944 for SPECT/CT). SPECT/CT increases accuracy of the diagnosis in the evaluation of OM when it is compared to three phase bone scintigraphy/SPECT. SPECT/CT can change the diagnosis and management of the patients.
ISSN:2146-1414
2147-1959
DOI:10.4274/mirt.galenos.2019.20053