Age-Specific Serum Total and Free Estradiol Concentrations in Healthy Men in US Nationally Representative Samples

To report age-specific serum estradiol concentration in nonsmoking, lean US men without comorbidities. We provide concentrations from 30 and 15 to 20 years ago given previously described declines in serum estradiol in US men over time. We used data from the Third National Health and Nutrition Examin...

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Bibliographic Details
Published in:Journal of the Endocrine Society 2019-10, Vol.3 (10), p.1825-1836
Main Authors: Chadid, Susan, Barber, John R, Rohrmann, Sabine, Nelson, William G, Yager, James D, Kanarek, Norma F, Bradwin, Gary, Dobs, Adrian S, McGlynn, Katherine A, Platz, Elizabeth A
Format: Article
Language:English
Subjects:
Clinical s
Estradiol
Physiological aspects
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Summary:To report age-specific serum estradiol concentration in nonsmoking, lean US men without comorbidities. We provide concentrations from 30 and 15 to 20 years ago given previously described declines in serum estradiol in US men over time. We used data from the Third National Health and Nutrition Examination Survey (NHANES III; 1988 to 1991) and continuous NHANES (1999 to 2004). Serum estradiol and SHBG were previously measured by competitive electrochemiluminescence immunoassays. Free estradiol was estimated from estradiol, SHBG, and albumin. By age, we calculated median concentrations overall and for nonsmoking, lean (body mass index
ISSN:2472-1972
2472-1972
DOI:10.1210/js.2019-00178