Chronic obstructive pulmonary disease combined with vertebral compression fracture increases the risk of temporomandibular disorder: A population-based cohort study

Vertebral compression fracture (VCF) is a common comorbidity of chronic obstructive pulmonary disease (COPD), and the coexistence of COPD and temporomandibular disorder (TMD) has been clinically noted. The present study aimed to investigate whether VCF increases the risk of TMD in patients with COPD...

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Bibliographic Details
Published in:Medicine (Baltimore) 2019-09, Vol.98 (37), p.e17162-e17162
Main Authors: Lee, Kuei-Chen, Wu, Yung-Tsan, Chen, Liang-Cheng, Shen, Chih-Hao, Chung, Chi-Hsiang, Chien, Wu-Chien, Shieh, Yi-Shing
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Comorbidity
Female
Fractures, Compression - complications
Fractures, Compression - epidemiology
Glucocorticoids - adverse effects
Glucocorticoids - therapeutic use
Humans
Longitudinal Studies
Male
Middle Aged
Observational Study
Prevalence
Pulmonary Disease, Chronic Obstructive - complications
Pulmonary Disease, Chronic Obstructive - epidemiology
Retrospective Studies
Risk Factors
Spinal Fractures - complications
Spinal Fractures - epidemiology
Temporomandibular Joint Disorders - complications
Temporomandibular Joint Disorders - epidemiology
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Summary:Vertebral compression fracture (VCF) is a common comorbidity of chronic obstructive pulmonary disease (COPD), and the coexistence of COPD and temporomandibular disorder (TMD) has been clinically noted. The present study aimed to investigate whether VCF increases the risk of TMD in patients with COPD.With a follow-up period of 15 years, this retrospective, population-based longitudinal cohort study enrolled sex- and age-matched COPD patients with and without VCF (1:3) who were identified from Taiwan's National Health Insurance Research Database from 2000 to 2015. Multivariate Cox regression analysis was performed to determine the risk of TMD in COPD patients with and without VCF. The cumulative risk of TMD between groups was estimated using Kaplan-Meier analysis.The risk factors for TMD in patients with COPD were VCF, osteoporosis, and winter season. The COPD with VCF group was more likely to develop TMD (adjusted hazard ratio = 3.011, P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000017162