Loading…

A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication

Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches are challenging. Methods and Materials For 10 patients requiri...

Full description

Saved in:
Bibliographic Details
Published in:Journal of applied clinical medical physics 2019-09, Vol.20 (9), p.78-85
Main Authors: Sasaki, David Kiyoshi, McGeachy, Philip, Alpuche Aviles, Jorge E., McCurdy, Boyd, Koul, Rashmi, Dubey, Arbind
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793
cites cdi_FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793
container_end_page 85
container_issue 9
container_start_page 78
container_title Journal of applied clinical medical physics
container_volume 20
creator Sasaki, David Kiyoshi
McGeachy, Philip
Alpuche Aviles, Jorge E.
McCurdy, Boyd
Koul, Rashmi
Dubey, Arbind
description Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches are challenging. Methods and Materials For 10 patients requiring bolus in regions with complex contours, bolus was designed digitally from 3D surface scanning data or computed tomography (CT) images using either a treatment planning system or mesh editing software. Boluses were printed using a fused deposition modeling printer with polylactic acid. Quality assurance tests were performed for each printed bolus to verify density and shape. Results For 9 of 10 patients, digitally designed boluses were used for treatment with no issues. In 1 case, the bolus was not used because dosimetric requirements were met without the bolus. QA tests revealed that the bulk density was within 3% of the reference value for 9 of 12 prints, and with more judicious selection of print settings this could be increased. For these 9 prints, density uniformity was as good as or better than our traditional sheet bolus material. The average shape error of the pieces was less than 0.5 mm, and no issues with fit or comfort were encountered during use. Conclusions This study demonstrates that new technologies such as 3D surface scanning, digital design and 3D printing can be safely and effectively used to modernize bolus fabrication.
doi_str_mv 10.1002/acm2.12703
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6753733</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2281117591</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793</originalsourceid><addsrcrecordid>eNp9kU1PHSEUhkljo9a66Q9oSNw0jVc5MDNAF01ubr9MNN20a8IAMxczAwozNf77Mr3WWBddQTgPDy95EXoD5AwIoefajPQMKCfsBTqEmjYrKaHae7I_QK9yviYEQDCxjw4YVHUFlThE_RqP0boUyjJYnGIcP-Arl7c-9Jh9wnlOnTYOZ6NDKGen2PreT3rA1mXfh1Osg13Am-TDtFy689MWt3GYM-50m7zRk4_hNXrZ6SG744f1CP388vnH5tvq8vvXi836cmUq3rCVMMQYW4FkptFNKzvBpeiA1EQ7xpnQoq2JZbSVzFEuLLQdM7xMhWmF45IdoY87783cjs4aF6akB1XSjTrdq6i9-ncS_Fb18ZdqeF0eYEXw7kGQ4u3s8qRGn40bBh1cnLOiVAAAryUU9OQZeh3nFMr3CiUZr4pzSfR-R5kUc06uewwDRC39qaU_9ae_Ar99Gv8R_VtYAWAH3PnB3f9HpdabK7qT_gah8KSF</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2293746759</pqid></control><display><type>article</type><title>A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>Open Access: Wiley-Blackwell Open Access Journals</source><source>PubMed Central(OA)</source><creator>Sasaki, David Kiyoshi ; McGeachy, Philip ; Alpuche Aviles, Jorge E. ; McCurdy, Boyd ; Koul, Rashmi ; Dubey, Arbind</creator><creatorcontrib>Sasaki, David Kiyoshi ; McGeachy, Philip ; Alpuche Aviles, Jorge E. ; McCurdy, Boyd ; Koul, Rashmi ; Dubey, Arbind</creatorcontrib><description>Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches are challenging. Methods and Materials For 10 patients requiring bolus in regions with complex contours, bolus was designed digitally from 3D surface scanning data or computed tomography (CT) images using either a treatment planning system or mesh editing software. Boluses were printed using a fused deposition modeling printer with polylactic acid. Quality assurance tests were performed for each printed bolus to verify density and shape. Results For 9 of 10 patients, digitally designed boluses were used for treatment with no issues. In 1 case, the bolus was not used because dosimetric requirements were met without the bolus. QA tests revealed that the bulk density was within 3% of the reference value for 9 of 12 prints, and with more judicious selection of print settings this could be increased. For these 9 prints, density uniformity was as good as or better than our traditional sheet bolus material. The average shape error of the pieces was less than 0.5 mm, and no issues with fit or comfort were encountered during use. Conclusions This study demonstrates that new technologies such as 3D surface scanning, digital design and 3D printing can be safely and effectively used to modernize bolus fabrication.</description><identifier>ISSN: 1526-9914</identifier><identifier>EISSN: 1526-9914</identifier><identifier>DOI: 10.1002/acm2.12703</identifier><identifier>PMID: 31454148</identifier><language>eng</language><publisher>United States: John Wiley &amp; Sons, Inc</publisher><subject>3-D printers ; 3D printing ; 3D scanning ; Accuracy ; Aged ; Aged, 80 and over ; bolus ; Carcinoma, Basal Cell - diagnostic imaging ; Carcinoma, Basal Cell - radiotherapy ; Carcinoma, Squamous Cell - diagnostic imaging ; Carcinoma, Squamous Cell - radiotherapy ; Design ; digital design ; Equipment Design ; Female ; Humans ; Image Processing, Computer-Assisted - methods ; Male ; Middle Aged ; mold room ; Organs at Risk - radiation effects ; Patients ; Printing, Three-Dimensional - instrumentation ; Prognosis ; Quality Assurance, Health Care - standards ; Quality control ; Radiation Oncology Physics ; Radiation therapy ; Radiotherapy Dosage ; Radiotherapy Planning, Computer-Assisted - methods ; Radiotherapy, Intensity-Modulated - instrumentation ; Radiotherapy, Intensity-Modulated - methods ; Scanners ; Skin Neoplasms - diagnostic imaging ; Skin Neoplasms - radiotherapy ; Software ; Tomography, X-Ray Computed - methods ; Tumors</subject><ispartof>Journal of applied clinical medical physics, 2019-09, Vol.20 (9), p.78-85</ispartof><rights>2019 The Authors. published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.</rights><rights>2019 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.</rights><rights>2019. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793</citedby><cites>FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2293746759/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2293746759?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,11562,25753,27924,27925,37012,37013,44590,46052,46476,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31454148$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sasaki, David Kiyoshi</creatorcontrib><creatorcontrib>McGeachy, Philip</creatorcontrib><creatorcontrib>Alpuche Aviles, Jorge E.</creatorcontrib><creatorcontrib>McCurdy, Boyd</creatorcontrib><creatorcontrib>Koul, Rashmi</creatorcontrib><creatorcontrib>Dubey, Arbind</creatorcontrib><title>A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication</title><title>Journal of applied clinical medical physics</title><addtitle>J Appl Clin Med Phys</addtitle><description>Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches are challenging. Methods and Materials For 10 patients requiring bolus in regions with complex contours, bolus was designed digitally from 3D surface scanning data or computed tomography (CT) images using either a treatment planning system or mesh editing software. Boluses were printed using a fused deposition modeling printer with polylactic acid. Quality assurance tests were performed for each printed bolus to verify density and shape. Results For 9 of 10 patients, digitally designed boluses were used for treatment with no issues. In 1 case, the bolus was not used because dosimetric requirements were met without the bolus. QA tests revealed that the bulk density was within 3% of the reference value for 9 of 12 prints, and with more judicious selection of print settings this could be increased. For these 9 prints, density uniformity was as good as or better than our traditional sheet bolus material. The average shape error of the pieces was less than 0.5 mm, and no issues with fit or comfort were encountered during use. Conclusions This study demonstrates that new technologies such as 3D surface scanning, digital design and 3D printing can be safely and effectively used to modernize bolus fabrication.</description><subject>3-D printers</subject><subject>3D printing</subject><subject>3D scanning</subject><subject>Accuracy</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>bolus</subject><subject>Carcinoma, Basal Cell - diagnostic imaging</subject><subject>Carcinoma, Basal Cell - radiotherapy</subject><subject>Carcinoma, Squamous Cell - diagnostic imaging</subject><subject>Carcinoma, Squamous Cell - radiotherapy</subject><subject>Design</subject><subject>digital design</subject><subject>Equipment Design</subject><subject>Female</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted - methods</subject><subject>Male</subject><subject>Middle Aged</subject><subject>mold room</subject><subject>Organs at Risk - radiation effects</subject><subject>Patients</subject><subject>Printing, Three-Dimensional - instrumentation</subject><subject>Prognosis</subject><subject>Quality Assurance, Health Care - standards</subject><subject>Quality control</subject><subject>Radiation Oncology Physics</subject><subject>Radiation therapy</subject><subject>Radiotherapy Dosage</subject><subject>Radiotherapy Planning, Computer-Assisted - methods</subject><subject>Radiotherapy, Intensity-Modulated - instrumentation</subject><subject>Radiotherapy, Intensity-Modulated - methods</subject><subject>Scanners</subject><subject>Skin Neoplasms - diagnostic imaging</subject><subject>Skin Neoplasms - radiotherapy</subject><subject>Software</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>Tumors</subject><issn>1526-9914</issn><issn>1526-9914</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>PIMPY</sourceid><recordid>eNp9kU1PHSEUhkljo9a66Q9oSNw0jVc5MDNAF01ubr9MNN20a8IAMxczAwozNf77Mr3WWBddQTgPDy95EXoD5AwIoefajPQMKCfsBTqEmjYrKaHae7I_QK9yviYEQDCxjw4YVHUFlThE_RqP0boUyjJYnGIcP-Arl7c-9Jh9wnlOnTYOZ6NDKGen2PreT3rA1mXfh1Osg13Am-TDtFy689MWt3GYM-50m7zRk4_hNXrZ6SG744f1CP388vnH5tvq8vvXi836cmUq3rCVMMQYW4FkptFNKzvBpeiA1EQ7xpnQoq2JZbSVzFEuLLQdM7xMhWmF45IdoY87783cjs4aF6akB1XSjTrdq6i9-ncS_Fb18ZdqeF0eYEXw7kGQ4u3s8qRGn40bBh1cnLOiVAAAryUU9OQZeh3nFMr3CiUZr4pzSfR-R5kUc06uewwDRC39qaU_9ae_Ar99Gv8R_VtYAWAH3PnB3f9HpdabK7qT_gah8KSF</recordid><startdate>201909</startdate><enddate>201909</enddate><creator>Sasaki, David Kiyoshi</creator><creator>McGeachy, Philip</creator><creator>Alpuche Aviles, Jorge E.</creator><creator>McCurdy, Boyd</creator><creator>Koul, Rashmi</creator><creator>Dubey, Arbind</creator><general>John Wiley &amp; Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M2P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>201909</creationdate><title>A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication</title><author>Sasaki, David Kiyoshi ; McGeachy, Philip ; Alpuche Aviles, Jorge E. ; McCurdy, Boyd ; Koul, Rashmi ; Dubey, Arbind</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>3-D printers</topic><topic>3D printing</topic><topic>3D scanning</topic><topic>Accuracy</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>bolus</topic><topic>Carcinoma, Basal Cell - diagnostic imaging</topic><topic>Carcinoma, Basal Cell - radiotherapy</topic><topic>Carcinoma, Squamous Cell - diagnostic imaging</topic><topic>Carcinoma, Squamous Cell - radiotherapy</topic><topic>Design</topic><topic>digital design</topic><topic>Equipment Design</topic><topic>Female</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted - methods</topic><topic>Male</topic><topic>Middle Aged</topic><topic>mold room</topic><topic>Organs at Risk - radiation effects</topic><topic>Patients</topic><topic>Printing, Three-Dimensional - instrumentation</topic><topic>Prognosis</topic><topic>Quality Assurance, Health Care - standards</topic><topic>Quality control</topic><topic>Radiation Oncology Physics</topic><topic>Radiation therapy</topic><topic>Radiotherapy Dosage</topic><topic>Radiotherapy Planning, Computer-Assisted - methods</topic><topic>Radiotherapy, Intensity-Modulated - instrumentation</topic><topic>Radiotherapy, Intensity-Modulated - methods</topic><topic>Scanners</topic><topic>Skin Neoplasms - diagnostic imaging</topic><topic>Skin Neoplasms - radiotherapy</topic><topic>Software</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sasaki, David Kiyoshi</creatorcontrib><creatorcontrib>McGeachy, Philip</creatorcontrib><creatorcontrib>Alpuche Aviles, Jorge E.</creatorcontrib><creatorcontrib>McCurdy, Boyd</creatorcontrib><creatorcontrib>Koul, Rashmi</creatorcontrib><creatorcontrib>Dubey, Arbind</creatorcontrib><collection>Open Access: Wiley-Blackwell Open Access Journals</collection><collection>Wiley-Blackwell Free Backfiles(OpenAccess)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Science Journals (ProQuest Database)</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of applied clinical medical physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sasaki, David Kiyoshi</au><au>McGeachy, Philip</au><au>Alpuche Aviles, Jorge E.</au><au>McCurdy, Boyd</au><au>Koul, Rashmi</au><au>Dubey, Arbind</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication</atitle><jtitle>Journal of applied clinical medical physics</jtitle><addtitle>J Appl Clin Med Phys</addtitle><date>2019-09</date><risdate>2019</risdate><volume>20</volume><issue>9</issue><spage>78</spage><epage>85</epage><pages>78-85</pages><issn>1526-9914</issn><eissn>1526-9914</eissn><abstract>Purpose This case series represents an initial experience with implementing 3‐dimensional (3D) surface scanning, digital design, and 3D printing for bolus fabrication for patients with complex surface anatomy where traditional approaches are challenging. Methods and Materials For 10 patients requiring bolus in regions with complex contours, bolus was designed digitally from 3D surface scanning data or computed tomography (CT) images using either a treatment planning system or mesh editing software. Boluses were printed using a fused deposition modeling printer with polylactic acid. Quality assurance tests were performed for each printed bolus to verify density and shape. Results For 9 of 10 patients, digitally designed boluses were used for treatment with no issues. In 1 case, the bolus was not used because dosimetric requirements were met without the bolus. QA tests revealed that the bulk density was within 3% of the reference value for 9 of 12 prints, and with more judicious selection of print settings this could be increased. For these 9 prints, density uniformity was as good as or better than our traditional sheet bolus material. The average shape error of the pieces was less than 0.5 mm, and no issues with fit or comfort were encountered during use. Conclusions This study demonstrates that new technologies such as 3D surface scanning, digital design and 3D printing can be safely and effectively used to modernize bolus fabrication.</abstract><cop>United States</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>31454148</pmid><doi>10.1002/acm2.12703</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1526-9914
ispartof Journal of applied clinical medical physics, 2019-09, Vol.20 (9), p.78-85
issn 1526-9914
1526-9914
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6753733
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); Open Access: Wiley-Blackwell Open Access Journals; PubMed Central(OA)
subjects 3-D printers
3D printing
3D scanning
Accuracy
Aged
Aged, 80 and over
bolus
Carcinoma, Basal Cell - diagnostic imaging
Carcinoma, Basal Cell - radiotherapy
Carcinoma, Squamous Cell - diagnostic imaging
Carcinoma, Squamous Cell - radiotherapy
Design
digital design
Equipment Design
Female
Humans
Image Processing, Computer-Assisted - methods
Male
Middle Aged
mold room
Organs at Risk - radiation effects
Patients
Printing, Three-Dimensional - instrumentation
Prognosis
Quality Assurance, Health Care - standards
Quality control
Radiation Oncology Physics
Radiation therapy
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted - methods
Radiotherapy, Intensity-Modulated - instrumentation
Radiotherapy, Intensity-Modulated - methods
Scanners
Skin Neoplasms - diagnostic imaging
Skin Neoplasms - radiotherapy
Software
Tomography, X-Ray Computed - methods
Tumors
title A modern mold room: Meshing 3D surface scanning, digital design, and 3D printing with bolus fabrication
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T05%3A42%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20modern%20mold%20room:%20Meshing%203D%20surface%20scanning,%20digital%20design,%20and%203D%20printing%20with%20bolus%20fabrication&rft.jtitle=Journal%20of%20applied%20clinical%20medical%20physics&rft.au=Sasaki,%20David%20Kiyoshi&rft.date=2019-09&rft.volume=20&rft.issue=9&rft.spage=78&rft.epage=85&rft.pages=78-85&rft.issn=1526-9914&rft.eissn=1526-9914&rft_id=info:doi/10.1002/acm2.12703&rft_dat=%3Cproquest_pubme%3E2281117591%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c4763-8c0ccd4193c6a6b9f8798f1050ae3738a8b50d32b93e278d1bf3c750a8cb8e793%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2293746759&rft_id=info:pmid/31454148&rfr_iscdi=true