Nilotinib-induced metabolic dysfunction: insights from a translational study using in vitro adipocyte models and patient cohorts

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Bibliographic Details
Published in:Leukemia 2019-07, Vol.33 (7), p.1810-1814
Main Authors: Sadiq, Soban, Owen, Euan, Foster, Terry, Knight, Katy, Wang, Lihui, Pirmohamed, Munir, Clark, Richard E., Pushpakom, Sudeep
Format: Article
Language:English
Subjects:
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14
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692/308/575
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Adipocytes - drug effects
Adipocytes - metabolism
Adipocytes - pathology
Adult
Cancer Research
Cells, Cultured
Cohort Studies
Critical Care Medicine
Female
Glucose - metabolism
Hematology
Humans
In Vitro Techniques
Intensive
Internal Medicine
Letter
Lipids - analysis
Male
Medicine
Medicine & Public Health
Middle Aged
Oncology
Pyrimidines - pharmacology
Translational Research, Biomedical
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ISSN:0887-6924
1476-5551
DOI:10.1038/s41375-018-0337-0