The Dynamics of Neuronal Death: A Time-Lapse Study in the Retina

Using time-lapse video microscopy, we have followed the process of neuronal death in an intact region of the mammalian nervous system. We show here the fast dynamics of nuclear fragmentation, which is over in

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Bibliographic Details
Published in:The Journal of neuroscience 2000-08, Vol.20 (16), p.92-RC92
Main Authors: Cellerino, Alessandro, Galli-Resta, Lucia, Colombaioni, Laura
Format: Article
Language:English
Subjects:
Amidines
Aniline Compounds
Animals
Animals, Newborn
Apoptosis - physiology
Calcium - metabolism
Cell Adhesion - physiology
Cell Movement - physiology
DNA Fragmentation - physiology
Fluorescent Dyes
In Vitro Techniques
Intracellular Fluid - metabolism
Microscopy, Video
Neurons - cytology
Neurons - metabolism
Rapid Communication
Rats
Rats, Long-Evans
Retina - cytology
Retina - physiology
Retinal Ganglion Cells - cytology
Retinal Ganglion Cells - physiology
Time Factors
Xanthenes
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Description
Summary:Using time-lapse video microscopy, we have followed the process of neuronal death in an intact region of the mammalian nervous system. We show here the fast dynamics of nuclear fragmentation, which is over in
ISSN:0270-6474
1529-2401
DOI:10.1523/jneurosci.20-16-j0002.2000