Role of Magnetic Resonance Imaging in Classifying Individuals Who Will Develop Accelerated Radiographic Knee Osteoarthritis

ABSTRACT We assessed whether adding magnetic resonance (MR)‐based features to a base model of clinically accessible participant characteristics (i.e., serological, radiographic, demographic, symptoms, and physical function) improved classification of adults who developed accelerated radiographic kne...

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Bibliographic Details
Published in:Journal of orthopaedic research 2019-11, Vol.37 (11), p.2420-2428
Main Authors: Price, Lori Lyn, Harkey, Matthew S., Ward, Robert J., MacKay, James W., Zhang, Ming, Pang, Jincheng, Davis, Julie E., McAlindon, Timothy E., Lo, Grace H., Amin, Mamta, Eaton, Charles B., Lu, Bing, Duryea, Jeffrey, Barbe, Mary F., Driban, Jeffrey B.
Format: Article
Language:English
Subjects:
Aged
Case-Control Studies
cruciate ligaments
effusion
Female
glucose
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Models, Theoretical
Osteoarthritis, Knee - diagnostic imaging
Risk Assessment
synovitis
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Summary:ABSTRACT We assessed whether adding magnetic resonance (MR)‐based features to a base model of clinically accessible participant characteristics (i.e., serological, radiographic, demographic, symptoms, and physical function) improved classification of adults who developed accelerated radiographic knee osteoarthritis (AKOA) or not over the subsequent 4 years. We conducted a case–control study using radiographs from baseline and the first four annual visits of the osteoarthritis initiative to define groups. Eligible individuals had no radiographic KOA in either knee at baseline (Kellgren–Lawrence [KL] grade 
ISSN:0736-0266
1554-527X
DOI:10.1002/jor.24413