A Rare Manifestation of Cervical Yolk Sac Tumor in an Unfortunate Infant

Paediatric germ cell tumor is composed of various neoplasms which exhibit capricious clinical presentation and histological features depending on the age and the area of presentation. Yolk sac tumor is an extremely rare malignant tumor of embryonic origin which usually arises from the gonads. Its ma...

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Bibliographic Details
Published in:Turkish Archives of Otorhinolaryngology 2019-09, Vol.57 (3), p.157-160
Main Authors: Saniasiaya, Jeyasakthy, Ab Hamid, Suzina Sheikh, Mohamad, Hazama, Wan Abdul Wahab, Wan Nur Najmiyah, Zawawi, Norzaliana
Format: Article
Language:English
Subjects:
Case Report
germ cell tumor
malignant transformation
teratoma
yolk sac tumor
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Summary:Paediatric germ cell tumor is composed of various neoplasms which exhibit capricious clinical presentation and histological features depending on the age and the area of presentation. Yolk sac tumor is an extremely rare malignant tumor of embryonic origin which usually arises from the gonads. Its manifestation in the head and neck region is extremely rare. Here, we report a rare case of the malignant transformation of mature teratoma into yolk sac tumor of the neck in an infant. Diagnosis was confirmed following histopathological examination of the neck mass along with marked increase of the serum alpha-fetoprotein. The child unfortunately succumbed prior to chemotherapy. We highlight the challenge we faced in diagnosing and managing this rare entity. We would also like to recommend serial monitoring of serum alpha-fetoprotein in all patients with mature teratoma to detect malignant transformation early.
ISSN:2667-7466
2667-7474
2667-7474
DOI:10.5152/tao.2019.3900