A rare case of cancer-to-cancer metastasis: breast cancer to renal cell cancer: Case report and review of literature

Summary Background Cancer-to-cancer metastasis is very rare with less than 50 cases described in literature. This article reports a case of breast cancer with synchronous metastasis to clear cell renal cell cancer. Case description A 79-year-old woman was diagnosed with a bilateral breast carcinoma....

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Bibliographic Details
Published in:Wiener medizinische Wochenschrift 2019-10, Vol.169 (13-14), p.350-353
Main Authors: Lakovschek, Ioana-Claudia, Petru, Edgar, Pollheimer, Marion J., Ratschek, Manfred, Augustin, Herbert, Bjelic-Radisic, Vesna
Format: Article
Language:English
Subjects:
Case Report
Family Medicine
General Practice
Geriatrics/Gerontology
Infectious Diseases
Internal Medicine
Medicine
Medicine & Public Health
Pharmacology/Toxicology
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Summary:Summary Background Cancer-to-cancer metastasis is very rare with less than 50 cases described in literature. This article reports a case of breast cancer with synchronous metastasis to clear cell renal cell cancer. Case description A 79-year-old woman was diagnosed with a bilateral breast carcinoma. Sonographic staging investigation of the abdomen revealed a 6 cm wide expansion of the right kidney. Bilateral mastectomy and nephrectomy of the right kidney was performed. The histology revealed a clear cell renal cell carcinoma and in the center of the tumor a 0.5 cm metastasis of the breast cancer. The patient’s comorbidities and performance status precluded chemotherapy und she received palliative radiotherapy, targeted monoclonal antibody therapy and antihormonal treatment. Conclusions Even if cancer-to-cancer metastasis is a very rare phenomenon, the simultaneous or consecutive finding of a renal tumor in women with breast cancer should be carefully evaluated.
ISSN:0043-5341
1563-258X
DOI:10.1007/s10354-019-0694-y