Intrauterine insemination as a primary viable option to infertile couples: evaluation of patients in a private center

• Published in: JBRA assisted reproduction 2019, Vol.23 (4), p.328-332
• Main Authors: Bonow, Marília Porto, Donne, Ricardo Ditzel Delle, Rosa, Vinicius Bonato da, Lucca, José Augusto, Hillesheim, Cristian Maio, Schuffner, Alessandro
• Format: Article
• Language: English
• Subjects: Adult; Artificial insemination; Couples; Female; Follicle Stimulating Hormone - blood; Humans; Infertility; Insemination, Artificial - methods; Male; Motility; Obstetrics; Original; Ovulation Induction; Patients; Pregnancy; Pregnancy Rate; Reproductive technologies; Retrospective Studies; Sperm; Sperm Motility; Success; Ultrasonic imaging
• ISSN: 1518-0557; 1517-5693; 1518-0557
• DOI: 10.5935/1518-0557.20190014

This study aimed to identify which parameters positively affect the clinical pregnancy rates of IUI cycles and find which couples should opt for IUI. This retrospective observational study included 261 patients submitted to 381 IUI cycles with fresh or cryopreserved partner semen (IU-H) from January 2012 to February 2017 in a private center in Curitiba-PR, Brazil. Idiopathic infertility was the most frequent finding (35.9%). Patients younger than 40 years accounted for 87.9% of the IUI cycles (n=335) and 16.1% of the clinical pregnancies (n=54). The pregnancy rate was three times higher in patients with an endometrium thickness ≥8 mm compared to patients with endometrium thickness 55% was linked to higher pregnancy rates (p=0.002). Concerning gonadotropins, 159 (48.4%) took rFSH, 127 (38.7%) hMG, and 42 (12.8%) uFSH, with pregnancy rates of 21.3%, 10.4% and 10.5%, respectively. Patients under 40 years of age with endometrium thickness ≥8 mm, sperm motility >55%, and on rFSH had significantly higher pregnancy rates (p