The establishment of biological reference intervals of nontraditional glycemic markers in a Chinese population

Background We established the reference intervals for glycated albumin (GA), fructosamine (FA), and 1,5‐anhydroglucitol (1,5‐AG) in a Chinese healthy population. Methods This study enrolled a total of 458 eligible reference individuals, consisted of 226 men and 232 women, aged from 20~79 years (medi...

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Bibliographic Details
Published in:Journal of clinical laboratory analysis 2017-09, Vol.31 (5), p.e22097-n/a
Main Authors: Zhou, Qiang, Shi, De‐Bao, Lv, Li‐Ying
Format: Article
Language:English
Subjects:
1,5‐anhydroglucitol
Adult
Age
Aged
Albumin
Asian Continental Ancestry Group - statistics & numerical data
Biomarkers - blood
Blood Chemical Analysis - standards
Blood Chemical Analysis - statistics & numerical data
Blood Glucose - analysis
Deoxyglucose - blood
Female
Females
fructosamine
Fructosamine - blood
glycated albumin
Humans
Male
Males
Middle Aged
Population studies
reference intervals
Reference Values
Serum Albumin - analysis
Statistical analysis
Young Adult
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Summary:Background We established the reference intervals for glycated albumin (GA), fructosamine (FA), and 1,5‐anhydroglucitol (1,5‐AG) in a Chinese healthy population. Methods This study enrolled a total of 458 eligible reference individuals, consisted of 226 men and 232 women, aged from 20~79 years (median age 43 years), who attending routine healthy checks. We stratified the subjects according to gender (males and females) and age (20‐39, 40‐59, and 60‐79 years), and combined statistical methods with Lahti algorithm, as well as appropriate clinical consideration, to judge whether partitioning for data was needed. Results Glycated albumin levels between males and females were statistically different (P
ISSN:0887-8013
1098-2825
DOI:10.1002/jcla.22097