A Comparison Study Between Point‐of‐Care Testing Systems and Central Laboratory for Determining Blood Glucose in Venous Blood

Background Diabetes mellitus is a metabolic disease that is characterized by hyperglycemia. Blood glucose (BG) is helpful for the diagnosis and treatment of diabetes and an important part of the management of diabetes. Point‐of‐care testing (POCT) is generally used by patients themselves or medical...

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Bibliographic Details
Published in:Journal of clinical laboratory analysis 2017-05, Vol.31 (3), p.n/a
Main Authors: Wei, Huiping, Lan, Fang, He, Qitian, Li, Haiwei, Zhang, Fuyong, Qin, Xue, Li, Shan
Format: Article
Language:English
Subjects:
accuracy
Adolescent
Adult
Aged
blood glucose
Blood Glucose - analysis
Blood tests
clinical laboratory
Diabetes
Diabetes mellitus
Female
Glucose
Humans
Hyperglycemia
Laboratories
Laboratories - standards
Linear Models
Male
Medical personnel
Middle Aged
Point-of-Care Testing - standards
point‐of‐care testing
Reproducibility of Results
Standardization
Young Adult
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Summary:Background Diabetes mellitus is a metabolic disease that is characterized by hyperglycemia. Blood glucose (BG) is helpful for the diagnosis and treatment of diabetes and an important part of the management of diabetes. Point‐of‐care testing (POCT) is generally used by patients themselves or medical personnel to monitor BG. The objective of this article was to evaluate the accuracy and consistency of POCT on venous blood samples and compare it with the central laboratory system to determine the reliability of POCT measurement results as diagnostic criteria. Method A total of 162 venous whole blood samples were pooled in this study, which included different concentrations and were determined by three POCT systems randomly. The results were compared with the central laboratory system, which uses the Glucose GOD‐PAP method (HITACHI 7600‐120). The accuracy was evaluated by the International Organization for Standardization (ISO) 15197:2013. Result Bland‐Altman and Passing‐Bablok regression analysis showed three POCT systems that were comparable with the reference method (0.65, 95% CI: −0.57 to 1.86, Y = −0.11 + 0.95X for ACCU‐CHEK®Performa; 0.40, 95% CI: −1.3 to 2.1, Y = 0.036 + 0.96X for ACCU‐CHEK®Active; 0.70, 95% CI: −0.44 to 1.83, Y = −0.073 + 0.95X for OneTouch ®UltraVue). According to ISO 15197:2013, all POCT systems showed 100% of the results within 0.83 mmol/l (15 mg/dl) at BG concentrations
ISSN:0887-8013
1098-2825
DOI:10.1002/jcla.22051