Objective and Subjective Effects of a Prototype Nasal Dilator Strip on Sleep in Subjects with Chronic Nocturnal Nasal Congestion

Introduction This exploratory study characterized the performance of a nasal dilator strip with improved spring forces in lowering nasal resistance during sleep and reducing sleep-disordered breathing in subjects with difficulty sleeping due to chronic nocturnal nasal congestion. Methods Subjects ap...

Full description

Saved in:
Bibliographic Details
Published in:Advances in therapy 2019-07, Vol.36 (7), p.1657-1671
Main Authors: Wheatley, John R., Amis, Terence C., Lee, Sharon A., Ciesla, Renee, Shanga, Gilbert
Format: Article
Language:English
Subjects:
Adult
Aged
Cardiology
Cross-Over Studies
Dilatation - methods
Endocrinology
Female
Health technology assessment
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Nasal Obstruction - complications
Nasal Obstruction - therapy
Oncology
Original Research
Pharmacology/Toxicology
Polysomnography
Respiration
Rheumatology
Snoring - etiology
Snoring - therapy
Surveys and Questionnaires
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction This exploratory study characterized the performance of a nasal dilator strip with improved spring forces in lowering nasal resistance during sleep and reducing sleep-disordered breathing in subjects with difficulty sleeping due to chronic nocturnal nasal congestion. Methods Subjects applied the strip at bedtime for 28 days (active phase; n  = 70). Objective assessments included snoring variables, breathing route during sleep, and polysomnography measures compared with baseline. Nasal breathing, congestion, and sleep were measured subjectively using rating scales and questionnaires. During a crossover nasal resistance phase ( n  = 55), nasal resistance was measured using posterior rhinomanometry with the strip applied on one of two nights. Results In the active phase, breathing and sleep were perceived to improve, with less daytime sleepiness ( P 
ISSN:0741-238X
1865-8652
DOI:10.1007/s12325-019-00980-z