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Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial
AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial....
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Published in: | BMJ (Online) 2019-11, Vol.367, p.l5922-l5922 |
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description | AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial.Setting59 general practices in the Netherlands.Participants322 adults aged 50 and older with a chronic vestibular syndrome.InterventionsStand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712. |
doi_str_mv | 10.1136/bmj.l5922 |
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In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.</description><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1756-1833</identifier><identifier>DOI: 10.1136/bmj.l5922</identifier><identifier>PMID: 31690561</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><subject>Anxiety ; Compensation ; Evidence-based medicine ; Internet ; Internet access ; Intervention ; Older people ; Otology ; Patients ; Physical therapy ; Primary care ; Rehabilitation ; Systematic review ; Vertigo ; Vestibular system</subject><ispartof>BMJ (Online), 2019-11, Vol.367, p.l5922-l5922</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to</rights><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions 2019 BMJ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to 2019 BMJ</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b409t-8129d40c790be4d3d54558cfcd3aae67b08c51a54c17783b5b55702b796ce7f13</citedby><cites>FETCH-LOGICAL-b409t-8129d40c790be4d3d54558cfcd3aae67b08c51a54c17783b5b55702b796ce7f13</cites><orcidid>0000-0002-2746-4820</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bmj.com/content/367/bmj.l5922.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://bmj.com/content/367/bmj.l5922.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>112,113,230,314,780,784,885,3194,27924,27925,77594,77595</link.rule.ids></links><search><creatorcontrib>van Vugt, Vincent A</creatorcontrib><creatorcontrib>van der Wouden, Johannes C</creatorcontrib><creatorcontrib>Essery, Rosie</creatorcontrib><creatorcontrib>Yardley, Lucy</creatorcontrib><creatorcontrib>Twisk, Jos W R</creatorcontrib><creatorcontrib>van der Horst, Henriëtte E</creatorcontrib><creatorcontrib>Maarsingh, Otto R</creatorcontrib><title>Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial</title><title>BMJ (Online)</title><description>AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial.Setting59 general practices in the Netherlands.Participants322 adults aged 50 and older with a chronic vestibular syndrome.InterventionsStand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.</description><subject>Anxiety</subject><subject>Compensation</subject><subject>Evidence-based medicine</subject><subject>Internet</subject><subject>Internet access</subject><subject>Intervention</subject><subject>Older people</subject><subject>Otology</subject><subject>Patients</subject><subject>Physical therapy</subject><subject>Primary care</subject><subject>Rehabilitation</subject><subject>Systematic review</subject><subject>Vertigo</subject><subject>Vestibular system</subject><issn>0959-8138</issn><issn>1756-1833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><recordid>eNp1ksuOFCEUhitG43TGWfgGJLpwFj1yKajChYmZeJlkEje6JkBRXXRoKA_UmH7HeSjpS4yauOIEPj7-Q07TvCT4hhAm3prd9iZwSemTZkU6LtakZ-xps8KSy3VPWH_RXOW8xRhT1vVS8OfNBSNCYi7Iqnm8i8VBdAUZnd2AHlwu3ixBAwI3aeODL7r4FNFPXyak43As0lLQPO2zT2VyoOc9yss8JyhoTID0sISSkd5UIcfHSykMDs4OZCdI0ds_H8v7OEDaOeQj2rhYnQHNoG3x1r1DZQLnkIZdFULVpZ0_hLUpFkgh1LKA1-FF82zUIbur83rZfP_08dvtl_X91893tx_u16bFstRPoXJose0kNq4d2MBbzns72oFp7URncG850by1pOt6ZrjhvMPUdFJY142EXTbvT955MTWSdTWGDmoGv9OwV0l79fdJ9JPapAcleiopPgjenAWQfiz1F1RtyLoQdHRpyYoyQjknLRUVffUPuk0LxNrekWpbQYis1PWJspByBjf-DkOwOoyJqmOijmNS2dcn9rD1f-wXIeTAwg</recordid><startdate>20191105</startdate><enddate>20191105</enddate><creator>van Vugt, Vincent A</creator><creator>van der Wouden, Johannes C</creator><creator>Essery, Rosie</creator><creator>Yardley, Lucy</creator><creator>Twisk, Jos W R</creator><creator>van der Horst, Henriëtte E</creator><creator>Maarsingh, Otto R</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group 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based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial</title><author>van Vugt, Vincent A ; van der Wouden, Johannes C ; Essery, Rosie ; Yardley, Lucy ; Twisk, Jos W R ; van der Horst, Henriëtte E ; Maarsingh, Otto R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b409t-8129d40c790be4d3d54558cfcd3aae67b08c51a54c17783b5b55702b796ce7f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Anxiety</topic><topic>Compensation</topic><topic>Evidence-based medicine</topic><topic>Internet</topic><topic>Internet access</topic><topic>Intervention</topic><topic>Older people</topic><topic>Otology</topic><topic>Patients</topic><topic>Physical therapy</topic><topic>Primary care</topic><topic>Rehabilitation</topic><topic>Systematic review</topic><topic>Vertigo</topic><topic>Vestibular system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>van Vugt, Vincent A</creatorcontrib><creatorcontrib>van der Wouden, Johannes C</creatorcontrib><creatorcontrib>Essery, Rosie</creatorcontrib><creatorcontrib>Yardley, Lucy</creatorcontrib><creatorcontrib>Twisk, Jos W R</creatorcontrib><creatorcontrib>van der Horst, Henriëtte E</creatorcontrib><creatorcontrib>Maarsingh, Otto R</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ (Online)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>van Vugt, Vincent A</au><au>van der Wouden, Johannes C</au><au>Essery, Rosie</au><au>Yardley, Lucy</au><au>Twisk, Jos W R</au><au>van der Horst, Henriëtte E</au><au>Maarsingh, Otto R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial</atitle><jtitle>BMJ (Online)</jtitle><date>2019-11-05</date><risdate>2019</risdate><volume>367</volume><spage>l5922</spage><epage>l5922</epage><pages>l5922-l5922</pages><issn>0959-8138</issn><eissn>1756-1833</eissn><abstract>AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial.Setting59 general practices in the Netherlands.Participants322 adults aged 50 and older with a chronic vestibular syndrome.InterventionsStand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><pmid>31690561</pmid><doi>10.1136/bmj.l5922</doi><orcidid>https://orcid.org/0000-0002-2746-4820</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Anxiety Compensation Evidence-based medicine Internet Internet access Intervention Older people Otology Patients Physical therapy Primary care Rehabilitation Systematic review Vertigo Vestibular system |
title | Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial |
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