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Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial

AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial....

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Published in:BMJ (Online) 2019-11, Vol.367, p.l5922-l5922
Main Authors: van Vugt, Vincent A, van der Wouden, Johannes C, Essery, Rosie, Yardley, Lucy, Twisk, Jos W R, van der Horst, Henriëtte E, Maarsingh, Otto R
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container_title BMJ (Online)
container_volume 367
creator van Vugt, Vincent A
van der Wouden, Johannes C
Essery, Rosie
Yardley, Lucy
Twisk, Jos W R
van der Horst, Henriëtte E
Maarsingh, Otto R
description AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial.Setting59 general practices in the Netherlands.Participants322 adults aged 50 and older with a chronic vestibular syndrome.InterventionsStand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.
doi_str_mv 10.1136/bmj.l5922
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In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.</description><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1756-1833</identifier><identifier>DOI: 10.1136/bmj.l5922</identifier><identifier>PMID: 31690561</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><subject>Anxiety ; Compensation ; Evidence-based medicine ; Internet ; Internet access ; Intervention ; Older people ; Otology ; Patients ; Physical therapy ; Primary care ; Rehabilitation ; Systematic review ; Vertigo ; Vestibular system</subject><ispartof>BMJ (Online), 2019-11, Vol.367, p.l5922-l5922</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to</rights><rights>Published by the BMJ Publishing Group Limited. 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For permission to use (where not already granted under a licence) please go to 2019 BMJ</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b409t-8129d40c790be4d3d54558cfcd3aae67b08c51a54c17783b5b55702b796ce7f13</citedby><cites>FETCH-LOGICAL-b409t-8129d40c790be4d3d54558cfcd3aae67b08c51a54c17783b5b55702b796ce7f13</cites><orcidid>0000-0002-2746-4820</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://bmj.com/content/367/bmj.l5922.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://bmj.com/content/367/bmj.l5922.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>112,113,230,314,780,784,885,3194,27924,27925,77594,77595</link.rule.ids></links><search><creatorcontrib>van Vugt, Vincent A</creatorcontrib><creatorcontrib>van der Wouden, Johannes C</creatorcontrib><creatorcontrib>Essery, Rosie</creatorcontrib><creatorcontrib>Yardley, Lucy</creatorcontrib><creatorcontrib>Twisk, Jos W R</creatorcontrib><creatorcontrib>van der Horst, Henriëtte E</creatorcontrib><creatorcontrib>Maarsingh, Otto R</creatorcontrib><title>Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial</title><title>BMJ (Online)</title><description>AbstractObjectiveTo investigate the clinical effectiveness and safety of stand alone and blended internet based vestibular rehabilitation (VR) in the management of chronic vestibular syndromes in general practice.DesignPragmatic, three armed, parallel group, individually randomised controlled trial.Setting59 general practices in the Netherlands.Participants322 adults aged 50 and older with a chronic vestibular syndrome.InterventionsStand alone VR comprising a six week, internet based intervention with weekly online sessions and daily exercises (10-20 minutes a day). In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). 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In the blended VR group, the same internet based intervention was supplemented by face-to-face physiotherapy support (home visits in weeks 1 and 3). Participants in the usual care group received standard care from a general practitioner, without any restrictions.Main outcome measuresThe primary outcome was vestibular symptoms after six months as measured by the vertigo symptom scale-short form (VSS-SF range 0-60, clinically relevant difference ≥3 points). Secondary outcomes were dizziness related impairment, anxiety, depressive symptoms, subjective improvement of vestibular symptoms after three and six months, and adverse events.ResultsIn the intention-to-treat analysis, participants in the stand alone and blended VR groups had lower VSS-SF scores at six months than participants in the usual care group (adjusted mean difference −4.1 points, 95% confidence interval −5.8 to −2.5; and −3.5 points, −5.1 to −1.9, respectively). Similar differences in VSS-SF scores were seen at three months follow-up. Participants in the stand alone and blended VR groups also experienced less dizziness related impairment, less anxiety, and more subjective improvement of vestibular symptoms at three and six months. No serious adverse events related to online VR occurred during the trial.ConclusionStand alone and blended internet based VR are clinically effective and safe interventions to treat adults aged 50 and older with a chronic vestibular syndrome. Online VR is an easily accessible form of treatment, with the potential to improve care for an undertreated group of patients in general practice.Trial registrationNetherlands Trial Register NTR5712.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><pmid>31690561</pmid><doi>10.1136/bmj.l5922</doi><orcidid>https://orcid.org/0000-0002-2746-4820</orcidid><oa>free_for_read</oa></addata></record>
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subjects Anxiety
Compensation
Evidence-based medicine
Internet
Internet access
Intervention
Older people
Otology
Patients
Physical therapy
Primary care
Rehabilitation
Systematic review
Vertigo
Vestibular system
title Internet based vestibular rehabilitation with and without physiotherapy support for adults aged 50 and older with a chronic vestibular syndrome in general practice: three armed randomised controlled trial
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