Case report: painful exanthems caused by enterovirus D68 in an adolescent

Unlike other enteroviruses which can cause herpangina or hand-foot-and-mouth disease, enterovirus D68 (EV-D68) has usually been linked to respiratory and neurological problems in young children. Skin manifestations had rarely been described in current literatures. We report a 17-year-old girl with f...

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Bibliographic Details
Published in:Medicine (Baltimore) 2019-08, Vol.98 (33), p.e16493-e16493
Main Authors: Chang, Tu-Hsuan, Yang, Tzu-I, Hsu, Wei-Yun, Huang, Li-Min, Chang, Luan-Yin, Lu, Chun-Yi
Format: Article
Language:English
Subjects:
Acute Pain - pathology
Acute Pain - virology
Adolescent
Clinical Case Report
Enterovirus D, Human
Enterovirus Infections - pathology
Enterovirus Infections - virology
Exanthema - pathology
Exanthema - virology
Female
Humans
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Summary:Unlike other enteroviruses which can cause herpangina or hand-foot-and-mouth disease, enterovirus D68 (EV-D68) has usually been linked to respiratory and neurological problems in young children. Skin manifestations had rarely been described in current literatures. We report a 17-year-old girl with fever and painful skin rash over legs and soles for 9 days. Pitting edema was also noted below the knees. There was no respiratory tract or neurological symptoms in this patient. EV-D68 was detected from a throat swab by RT-PCR and confirmed to be subclade B3 by sequencing. Supportive management. The patient was afebrile after 9 days and got full recovery on the 23rd day at outpatient follow-up. To the best of our knowledge, this is the first report of EV-D68 infection with skin manifestations, clinical images, and detailed clinical course. Our findings in this particular case extend the understanding of the disease spectrum.
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000016493