Novel Antiplatelet Perioperative Bridging Protocol for Lung Lobectomy: A Case Report

Some patients with cardiac stents will need thoracic surgery during the dual antiplatelet therapy (DAPT) period. When surgery cannot be safely delayed to allow 1 year of uninterrupted DAPT, appropriate perioperative management of anticoagulation is critical. A patient treated with new drug-eluting s...

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Bibliographic Details
Published in:Permanente journal 2019, Vol.23 (4)
Main Authors: Ely, Sora, Dominguez, Dana A, Velotta, Jeffrey B
Format: Article
Language:English
Subjects:
Clinical Medicine
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Summary:Some patients with cardiac stents will need thoracic surgery during the dual antiplatelet therapy (DAPT) period. When surgery cannot be safely delayed to allow 1 year of uninterrupted DAPT, appropriate perioperative management of anticoagulation is critical. A patient treated with new drug-eluting stents and DAPT was concomitantly diagnosed with lung cancer and required a lobectomy. We describe the novel addition of ticagrelor (a short-acting oral antiplatelet agent) to eptifibatide (a short-acting intravenous antiplatelet agent) to bridge DAPT for surgery. This ticagrelor-eptifibatide perioperative bridge resulted in decreased preoperative hospitalization compared with eptifibatide alone. There were no associated perioperative cardiac or bleeding complications.
ISSN:1552-5767
1552-5775
DOI:10.7812/TPP/18.119