INNV-33. BARRIERS TO ACCRUAL AND ENROLLMENT IN BRAIN TUMOR TRIALS

Abstract BACKGROUND A major impediment to improving neuro-oncology outcomes is poor clinical trial accrual. METHODS We convened a multi-stakeholder group including Society for Neuro-Oncology, Response Assessment in Neuro-Oncology, patient advocacy groups, clinical trial cooperative groups, and other...

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Published in:Neuro-oncology (Charlottesville, Va.) Va.), 2019-11, Vol.21 (Supplement_6), p.vi137-vi137
Main Authors: Lee, Eudocia, Chukwueke, Ugonma, Hervey-Jumper, Shawn, DeGroot, John, Leone, Pablo, Armstrong, Terri, Chang, Susan, Arons, David, Oliver, Kathy, Verble, Kay, Musella, Al, Willmarth, Nicole, Alexander, Brian, Bates, Amanda, Doherty, Lisa, Galanis, Evanthia, Gaffey, Sarah, Halkin, Thomas, Friday, Bret, Fouladi, Maryam, Lin, Nancy, Macdonald, David, Mehta, Minesh, Penas-Prado, Marta, Vogelbaum, Michael, Sahebjam, Solmaz, Sandak, David, van den Bent, Martin, Weller, Michael, Reardon, David, Wen, Patrick
Format: Article
Language:English
Subjects:
Innovations in Patient Care
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Summary:Abstract BACKGROUND A major impediment to improving neuro-oncology outcomes is poor clinical trial accrual. METHODS We convened a multi-stakeholder group including Society for Neuro-Oncology, Response Assessment in Neuro-Oncology, patient advocacy groups, clinical trial cooperative groups, and other partners to determine how we can improve trial accrual. RESULTS We described selected factors contributing to poor trial accrual and possible solutions. We focused on patient and community factors, disparities, physician and provider factors, clinical trial factors, and site and organizational factors CONCLUSIONS We will implement strategies with the intent to double accrual to neuro-oncology trials over the next 5 years.
ISSN:1522-8517
1523-5866
DOI:10.1093/neuonc/noz175.574